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Paranoia
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==Treatment== Paranoid [[delusion]]s are often treated with [[Antipsychotic|antipsychotic medication]], which exert a medium effect size.<ref>{{cite journal | vauthors = Huhn M, Nikolakopoulou A, Schneider-Thoma J, Krause M, Samara M, Peter N, Arndt T, Bäckers L, Rothe P, Cipriani A, Davis J, Salanti G, Leucht S | display-authors = 6 | title = Comparative efficacy and tolerability of 32 oral antipsychotics for the acute treatment of adults with multi-episode schizophrenia: a systematic review and network meta-analysis | language = English | journal = Lancet | volume = 394 | issue = 10202 | pages = 939–951 | date = September 2019 | pmid = 31303314 | pmc = 6891890 | doi = 10.1016/S0140-6736(19)31135-3 }}</ref> [[Cognitive behavioral therapy]] (CBT) lessens paranoid delusions relative to control conditions according to a [[meta-analysis]].<ref>{{cite journal | vauthors = Mehl S, Werner D, Lincoln TM | title = Corrigendum: Does Cognitive Behavior Therapy for psychosis (CBTp) show a sustainable effect on delusions? A meta-analysis | journal = Frontiers in Psychology | volume = 10 | pages = 1868 | date = 2019-08-28 | pmid = 31555162 | pmc = 6724716 | doi = 10.3389/fpsyg.2019.01868 | doi-access = free }}</ref> A [[meta-analysis]] of 43 studies reported that [[metacognitive training]] (MCT) reduces (paranoid) delusions at a medium to large effect size relative to control conditions.<ref>{{cite journal | vauthors = Penney D, Sauvé G, Mendelson D, Thibaudeau É, Moritz S, Lepage M | title = Immediate and Sustained Outcomes and Moderators Associated With Metacognitive Training for Psychosis: A Systematic Review and Meta-analysis | journal = JAMA Psychiatry | date = March 2022 | volume = 79 | issue = 5 | pages = 417–429 | pmid = 35320347 | pmc = 8943641 | doi = 10.1001/jamapsychiatry.2022.0277 }}</ref>
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