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=== Disadvantages of preprints === The disadvantages of preprints could be summarized as: lack of [[Peer review|peer-review]], absence of quality (in controversy), concerns about premature data, media coverage not properly presenting the inherent uncertainty of preprints,<ref name="BesançonPeiffer-Smadja2020">{{cite journal|last1=Besançon|first1=Lonni|last2=Peiffer-Smadja|first2=Nathan|last3=Segalas|first3=Corentin|last4=Jiang|first4=Haiting|last5=Masuzzo|first5=Paola|last6=Smout|first6=Cooper|last7=Billy|first7=Eric|last8=Deforet|first8=Maxime|last9=Leyrat|first9=Clémence|title=Open Science Saves Lives: Lessons from the COVID-19 Pandemic|journal=BMC Medical Research Methodology|year=2020|volume=21|issue=1|page=117|doi=10.1186/s12874-021-01304-y|pmid=34090351|pmc=8179078 |doi-access=free }}</ref> risk of double citation (by publishing a peer-reviewed article, the preprint may also be cited), lack of ethical and statistical guidelines, lack of respect for [[Committee on Publication Ethics|COPE]] or [[ICMJE recommendations|ICMJE]] guidelines, breach of [[intellectual property]] regulations in some countries, possible harm to health in certain cases, information overload, breach of [[Ingelfinger rule]] (a strategy conducted to discourage dissemination of research reports before they are published in the journal), rush to post low-quality research.<ref name="auto"/>
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