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Primula veris
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==Chemical constituents== The roots of ''Primula veris'' contain several [[glycoside]]s of 5-methoxysalicylic methyl ester, such as primeverin<ref>See {{PubChem|3038513}} for chemical structure</ref> and primulaverin.<ref>See [http://www.rsc.org/Merck-Index/monograph/mono1500007867/primulaverin Merck Index monograph] for chemical details</ref> In the crude dried root, their phenolic [[aglycones]] are responsible for the typical odour reminiscent of [[methyl salicylate]] or [[anethole]]. The dried roots contain significant amounts of [[triterpene]] [[saponin]]s, such as primula acid I/II, while in the flower these constituents are located in the [[sepal]]s, and the dominating constituents are [[flavonoid]]s.<ref>{{cite book |editor1-last=Wichtl |editor1-first=Max |title=Herbal Drugs and Phytopharmaceuticals: A Handbook for Practice on a Scientific Basis |date=2004 |publisher=CRC Press |isbn=978-0-8493-1961-7 |page=473 }}</ref> Rare side effects of the saponins can be nausea or diarrhoea while some of the phenolic constituents are possibly responsible for [[allergy|allergic]] reactions.<ref>{{cite book |last1=Howard |first1=Michael |title=Traditional Folk Remedies: A Comprehensive Herbal |date=1987 |publisher=Century |isbn=978-0-7126-1731-4 |pages=128β129 }}</ref><ref>{{cite web | url = http://www.biotox.cz/toxikon/rostliny/glykosidy.php | title = Glykosidy | publisher = biotox.cz | language = cs}}</ref> The subspecies ''macrocalyx'', growing in Siberia, contains the phenolic compound [[riccardin C]].<ref>{{cite journal |last1=Kosenkova |first1=Yu. S. |last2=Polovinka |first2=M. P. |last3=Koarova |first3=N. I. |last4=Korchagina |first4=D. V. |last5=Kurochkina |first5=N. Yu. |last6=Cheremushkina |first6=V. A. |last7=Salakhutdinov |first7=N. F. |title=Seasonal Dynamics of Riccardin C Accumulation in Primula macrocalyx Bge |journal=Chemistry for Sustainable Development |volume=17 |year=2009 |pages=507β511 |citeseerx=10.1.1.1052.8459 }}</ref>
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