Editing Ragdoll (section)

==Health==
A UK study utilizing veterinary records found a life expectancy of 10.31 years compared to 11.74 overall.<ref>{{cite journal | last=Teng | first=Kendy Tzu-yun | last2=Brodbelt | first2=Dave C | last3=Church | first3=David B | last4=O’Neill | first4=Dan G | title=Life tables of annual life expectancy and risk factors for mortality in cats in the UK | journal=Journal of Feline Medicine and Surgery | volume=26 | issue=5 | date=2024 | issn=1098-612X | doi=10.1177/1098612X241234556 | page=| doi-access=free | pmc=11156239 }}</ref> One study, utilizing Swedish insurance data, showed that of the common cat breeds, the Ragdoll and Siamese have the lowest survival rate, with a 78% chance of survival to 10 years.<ref>{{Cite journal | last1 = Egenvall | first1 = A. | last2 = Nødtvedt | first2 = A. | last3 = Häggström | first3 = J. | last4 = Ström Holst | first4 = B. | last5 = Möller | first5 = L. | last6 = Bonnett | first6 = B. N. | title = Mortality of Life-Insured Swedish Cats during 1999–2006: Age, Breed, Sex, and Diagnosis | journal = Journal of Veterinary Internal Medicine | volume = 23 | issue = 6 | pages = 1175–1183 | year = 2009 | pmid = 19780926 | doi = 10.1111/j.1939-1676.2009.0396.x| pmc = 7167180 }}</ref> An English study of patient records found a life expectancy of 10.1 years.<ref>{{cite journal | last1=O’Neill | first1=Dan G | last2=Church | first2=David B | last3=McGreevy | first3=Paul D | last4=Thomson | first4=Peter C | last5=Brodbelt | first5=David C | title=Longevity and mortality of cats attending primary care veterinary practices in England | journal=Journal of Feline Medicine and Surgery | publisher=SAGE Publications | volume=17 | issue=2 | date=2014-06-12 | issn=1098-612X | doi=10.1177/1098612x14536176 | pages=125–133| pmid=24925771 | pmc=10816413 }}</ref> In a review of over 5,000 cases of [[Bladder stone (animal)|urate urolithiasis]], the Ragdoll was over-represented, with an odds ratio of 5.14.<ref name="pmid22443437">{{cite journal |last1=Albasan |first1=H. |last2=Osborne |first2=C. A. |last3=Lulich |first3=J. P. |last4=Lekcharoensuk |first4=C. |title=Risk factors for urate uroliths in cats. |journal=[[Journal of the American Veterinary Medical Association]] |date=2012 |volume=240 |issue=7 |pages=842–847 |pmid=22443437 |doi=10.2460/javma.240.7.842 |pmc= |url= https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22443437}}</ref> An English study reviewing over 190,000 patient records found the Ragdoll to be less likely to acquire [[diabetes mellitus]] than mixed breed cats. The prevalence in Ragdolls was 0.24% compared to 0.58% overall.<ref>{{cite journal | last1=O'Neill | first1=D.G. | last2=Gostelow | first2=R. | last3=Orme | first3=C. | last4=Church | first4=D.B. | last5=Niessen | first5=S.J.M. | last6=Verheyen | first6=K. | last7=Brodbelt | first7=D.C. | title=Epidemiology of Diabetes Mellitus among 193,435 Cats Attending Primary-Care Veterinary Practices in England | journal=Journal of Veterinary Internal Medicine | publisher=Wiley | volume=30 | issue=4 | date=2016-06-29 | issn=0891-6640 | doi=10.1111/jvim.14365 | pages=964–972| pmid=27353396 | pmc=5094533 }}</ref>
===Hypertrophic cardiomyopathy===
The Ragdoll is one of the more commonly affected breeds for [[hypertrophic cardiomyopathy]]. An [[autosomal dominant]] mutation of the [[MYBPC (disambiguation)|MYBPC]] group of genes is responsible for the condition in the breed.<ref>{{cite book |author1-first=James A.C. |author1-last=Oliver |author2-first=Cathryn S. |author2-last=Mellersh | editor1-first=Barbara | editor1-last=Cooper | editor2-first=Elizabeth |editor2-last=Mullineaux |editor3-first=Lynn | editor3-last=Turner |title=BSAVA Textbook of Veterinary Nursing |date=2020 |publisher=British Small Animal Veterinary Association |isbn=978-1-910-44339-2 |edition=Sixth|chapter=Genetics| page=131}}</ref>

The [[allele|allelic frequencies]] of the mutation R820W were 0.17 in cats from Italy and 0.23 in cats from the US in 2013.<ref name="vetogene.it">{{cite web|url=http://www.vetogene.it/GATTI/upload/jvim12031.pdf|title=Myosin-Binding Protein C DNA Variants in Domestic Cats (A31P, A74T, R820W) and Their Association with Hypertrophic Cardiomyopathy|publisher=Vetogene.it|access-date=15 December 2017|archive-date=11 February 2015|archive-url=https://web.archive.org/web/20150211222112/http://www.vetogene.it/GATTI/upload/jvim12031.pdf|url-status=dead}}</ref> This reference states that the R820W prevalence is 30% in the UK.<ref>{{cite web|url=http://www.fabcats.org/hcm/|title=Hypertrophic cardiomyopathy (HCM) in cats|website=Fabcats.org|access-date=15 December 2017}}</ref> The HCM prevalence was found to be 2.9% (95% CI = 2.7–8.6%) in this study.<ref name="vetogene.it"/>