Editing Recurrent miscarriage (section)

=== Thrombophilia ===

An important example is the possible increased risk of miscarriage in women with [[thrombophilia]] (propensity for [[thrombosis|blood clots]]). The most common problem is the [[factor V Leiden]] and [[prothrombin G20210A]] [[mutation]].<ref name=ACOG2001/> Some preliminary studies suggest that [[anticoagulant]] medication may improve the chances of carrying pregnancy to term but these studies need to be confirmed before they are adopted in clinical practice.<ref name="Rodger">{{cite journal | vauthors = Rodger MA, Paidas M, McLintock C, Middeldorp S, Kahn S, Martinelli I, Hague W, Rosene Montella K, Greer I | display-authors = 6 | title = Inherited thrombophilia and pregnancy complications revisited | journal = Obstetrics and Gynecology | volume = 112 | issue = 2 Pt 1 | pages = 320–324 | date = August 2008 | pmid = 18669729 | doi = 10.1097/AOG.0b013e31817e8acc }}</ref> Note that many women with thrombophilia go through one or more pregnancies with no difficulties, while others may have pregnancy complications. Thrombophilia may explain up to 49–65% of recurrent miscarriages.<ref>{{cite journal | vauthors = Nahas R, Saliba W, Elias A, Elias M | title = The Prevalence of Thrombophilia in Women With Recurrent Fetal Loss and Outcome of Anticoagulation Therapy for the Prevention of Miscarriages | journal = Clinical and Applied Thrombosis/Hemostasis | volume = 24 | issue = 1 | pages = 122–128 | date = January 2018 | pmid = 27799457 | pmc = 6714626 | doi = 10.1177/1076029616675967 }}</ref>