Editing S-layer (section)

== Application ==
Native S-layer proteins have already been used three decades ago in the development of biosensors and ultrafiltration membranes.<ref name="Sleytr2014" /><ref name="Sleytr2025" /> Subsequently, S-layer fusion proteins with specific functional  domains (e.g. enzymes, ligands, mimotopes, antibodies or antigens) allowed to investigate completely new strategies for functionalizing surfaces in the life sciences, such as in the development of novel affinity matrices, mucosal vaccines, biocompatible surfaces, micro carriers and encapsulation systems, or in the material sciences as templates for biomineralization.<ref name="Sleytr2014" /><ref name="Sleytr2025" /><ref name="Ilk2011" /><ref name ="FEMS1997">{{cite journal |doi=10.1016/S0168-6445(97)00044-2 |vauthors=Sleytr U, Bayley H, Sára M, Breitwieser A, Küpcü S, Mader C, Weigert S, Unger F, Messner P, Jahn-Schmid B, Schuster B, Pum D, Douglas K, Clark N, Moore J, Winningham T, Levy S, Frithsen I, Pankovc J, Beale P, Gillis H, Choutov D, Martin K |title=Applications of S-layers |journal=FEMS Microbiol. Rev. |volume=20 |issue=1–2 |pages=151–75 |year=1997 |doi-broken-date=29 April 2025 |pmid=9276930}}</ref><ref name= " Qing2023" >{{cite journal | vauthors = Qing R, Xue MT, Zhao JY, Wu LD, Breitwieser A, Smorodina E, Schubert T, Azzellino G, Jin D, Kong J, Palacios T, Sleytr UB, Zhang SG |date=2023 | title= Scalable biomimetic sensing system with membrane receptor dual-monolayer probe and graphene transistor arrays | journal = Science Advances | volume = 9 | issue = 29 | pages = eadf1402 | doi=10.1126/sciadv.adf1402|pmid=37478177 |pmc=10361598 |bibcode=2023SciA....9F1402Q | hdl = 10852/108278 | hdl-access = free }}</ref>