Editing Shotgun sequencing (section)

=== Pros and cons ===
Proponents of this approach argue that it is possible to sequence the whole [[genome]] at once using large arrays of sequencers, which makes the whole process much more efficient than more traditional approaches. Detractors argue that although the technique quickly sequences large regions of DNA, its ability to correctly link these regions is suspect, particularly for eukaryotic genomes with repeating regions. As [[sequence assembly]] programs become more sophisticated and computing power becomes cheaper, it may be possible to overcome this limitation.<ref>{{Cite journal |last1=Pop |first1=Mihai |last2=Salzberg |first2=Steven L. |date=March 2008 |title=Bioinformatics challenges of new sequencing technology |journal=Trends in Genetics |volume=24 |issue=3 |pages=142–149 |doi=10.1016/j.tig.2007.12.006 |issn=0168-9525 |pmc=2680276 |pmid=18262676}}</ref>