Editing Streptococcus pneumoniae (section)

==Biotechnology==
Components from ''S. pneumoniae'' have been harnessed for a range of applications in biotechnology. Through engineering of surface molecules from this bacterium, proteins can be irreversibly linked using the [[sortase]] enzyme<ref>{{cite journal |author=Nikghalb, Kevyan D. |title=Expanding the Scope of Sortase-Mediated Ligations by Using Sortase Homologues |journal=ChemBioChem |volume=19 |issue=7 |pages=185–195 |year=2018 |pmid=29124839 |doi=10.1002/cbic.201700517 |s2cid=23874288 }}</ref> or using the SnoopTag/SnoopCatcher reaction.<ref>{{cite journal |author=Veggiani, Gianluca |title=Programmable polyproteams built using twin peptide superglues  |journal=PNAS |volume=113 |issue=5 |pages=1202–1207 |year=2014 |pmid=26787909 |doi=10.1073/pnas.1519214113 |pmc=4747704 |bibcode=2016PNAS..113.1202V |doi-access=free }}</ref> Various [[glycoside hydrolases]] have also been cloned from ''S. pneumoniae'' to help analysis of cell [[glycosylation]].<ref>{{cite journal |author=Gregg, Katie J |title=Structural Analysis of a Family 101 Glycoside Hydrolase in Complex with Carbohydrates Reveals Insights into Its Mechanism |journal=Journal of Biological Chemistry |volume=290 |issue=42 |pages=25657–69 |date=16 October 2015 |doi=10.1074/jbc.M115.680470 |doi-access=free |pmid=26304114 |pmc=4646209}}</ref>