Editing Two and a Half Men (section)

=== Recurring ===
The following appeared in recurring roles or story arcs spanning multiple episodes:
* [[Jane Lynch]] as the sarcastic Dr. Linda Freeman, originally Jake's child psychologist and later Charlie's regular psychiatrist who later also treats Alan and Walden (seasons 1, 3–9, 11)
* [[Ryan Stiles]] as Herb Melnick, a pediatrician who becomes Judith's second ex-husband (seasons 2, 4–10, 12)
* [[Rebecca McFarland]] as Leanne, Pavlov's bartender (seasons 1–10)
* [[J. D. Walsh (actor)|J. D. Walsh]] as Gordon, a pizza delivery guy who idolizes Charlie's lifestyle (seasons 1–4, 6–8)
* [[Emmanuelle Vaugier]] as Mia, Charlie's ex-fiancée (seasons 3, 5–7 9, and 12)
* [[Robert Wagner]] as Nathan Krunk (alias "Teddy Leopold"), Evelyn's fifth husband, thought to be Courtney's father, but later revealed to be a con artist (seasons 4–5)
* [[Ming-Na Wen]] as the Hon. Linda Harris, superior court judge, adjunct law professor and Charlie's girlfriend (season 5)
* [[Jenny McCarthy]] as Sylvia Fishman (alias "Courtney Leopold"), alleged daughter of Nathan Krunk (alias "Teddy Leopold") (seasons 5, 8–9)
* [[Martin Mull]] as Russell, Charlie's self-medicating pharmacist (seasons 6–10)
* [[Kelly Stables]] as Melissa, Alan's receptionist, who dates both Charlie and Alan (seasons 6–8)
* [[Tinashe Kachingwe]] as Celeste Burnette, Jake's girlfriend whose father strongly disapproves of their relationship (seasons 6–7)
* [[Graham Patrick Martin]] as Eldridge McElroy, Lyndsey's son and Jake's equally dim-witted best friend (seasons 7–9)
* [[Courtney Thorne-Smith]] as Lyndsey McElroy, Alan's on/off love interest from season seven on and his fiancée in season 12. In season 10, she has a one-night stand with Kandi (Alan's ex-wife) (seasons 7–12)
* [[Carl Reiner]] as Marty Pepper, Evelyn's boyfriend and later husband (seasons 7–8, 11)
* [[Judy Greer]] as Bridget, Walden's ex-wife (seasons 9–12); also played Myra Melnick, Herb Melnick's sister and Charlie's one-night fling (season 4)
* [[Mimi Rogers]] as Robin Schmidt, Walden's mother (season 9–12)
* [[Sophie Winkleman]] as Zoey Hyde-Tottingham-Pierce, Walden's love interest following his divorce from Bridget (seasons 9–10, 12)
* Talyan Wright as Ava Pierce, Zoey's seven-year-old daughter (seasons 9–10)
* [[Patton Oswalt]] as Billy Stanhope, Walden's former business partner who dates Bridget (seasons 9–10)
* [[Brooke D'Orsay]] as Kate, Walden's love interest (seasons 10–11); also played Robin, Charlie's sex partner (season 4, episode 16)
* [[Missi Pyle]] as Miss Dolores Pasternak, Jake's teacher (seasons 2, 7, 9 and 12; played by [[Alicia Witt]] in season 6)
* [[Macey Cruthird]] as Megan, Jake's math tutor and later girlfriend (seasons 8–9)
* [[D. B. Sweeney]] as Larry Martin, a good friend of Alan and Walden's, who incidentally, was Lyndsey's boyfriend after Alan (seasons 11–12)
* [[Miley Cyrus]] as Missi, an old family friend of Walden's, who becomes Jake's brief love interest (season 10)
* [[Odette Annable]] as Nicole, brief love interest of Walden and majority owner of a garage-based tech start-up Walden joins (season 11)
* [[Clark Duke]] as Barry Foster, Nicole's business partner who befriends Walden and pretends to be the new "half-man" after Jake moved to Japan (seasons 11–12)
* [[Aly Michalka]] as Brooke, Jenny's girlfriend (season 11)
* [[Kimberly Williams-Paisley]] as Gretchen Martin, Larry Martin's sister, who dates Alan while Larry is with Lyndsey (season 11) (also worked with [[Courtney Thorne-Smith]] on [[American Broadcasting Company|ABC]]'s ''[[According to Jim]]'' as her TV sister)
* [[Maggie Lawson]] as Ms. McMartin, Walden and Alan's social worker for Louis' adoption (season 12)