Editing Candida albicans (section)

===White-GUT switch===
A very special type of phenotypic switch is the white-GUT switch (Gastrointestinally-IndUced Transition). GUT cells are extremely adapted to survival in the digestive tract by metabolic adaptations to available nutrients in the digestive tract. The GUT cells live as commensal organisms and outcompete other phenotypes. The transition from white to GUT cells is driven by passage through the gut where environmental parameters trigger this transition by increasing the WOR1 expression.<ref>{{cite journal | vauthors = Pande K, Chen C, Noble SM | title = Passage through the mammalian gut triggers a phenotypic switch that promotes Candida albicans commensalism | journal = Nature Genetics | volume = 45 | issue = 9 | pages = 1088–1091 | date = September 2013 | pmid = 23892606 | pmc = 3758371 | doi = 10.1038/ng.2710 }}</ref><ref>{{cite journal | vauthors = Noble SM, Gianetti BA, Witchley JN | title = Candida albicans cell-type switching and functional plasticity in the mammalian host | journal = Nature Reviews. Microbiology | volume = 15 | issue = 2 | pages = 96–108 | date = February 2017 | pmid = 27867199 | pmc = 5957277 | doi = 10.1038/nrmicro.2016.157 }}</ref>