Editing Cannabinol (section)

==History==
[[File:Brief History of CBN (Emphasis on US Legislation).png|thumb|400x400px|This timeline represents a simplified history of CBN with an emphasis on the complexity surrounding cannabis legislation in the US.|left]]

CBN was the first cannabinoid to be isolated from [[cannabis]] extract in the late 1800s. Specifically, it was discovered by Barlow Wood, Newton Spivey, and [[Thomas Easterfield|Easterfield]] in 1896.<ref>{{cite journal | vauthors = Wood TB, Spivey WN, Easterfield III TH | url=https://pubs.rsc.org/en/content/articlelanding/1899/ct/ct8997500020 | doi=10.1039/CT8997500020 | title=III.—Cannabinol. Part I | date=1899 | journal = Journal of the Chemical Society, Transactions | volume=75 | pages=20–36 }}</ref> In the early 1930s, CBN's structure was identified by [[Robert Sidney Cahn|Cahn]],<ref>{{cite journal | url=https://pubs.rsc.org/en/content/articlelanding/1932/jr/jr9320001342 | doi=10.1039/JR9320001342 | title=174. Cannabis indica resin. Part III. The constitution of cannabinol | date=1932 | last1=Cahn | first1=Robert Sidney | journal=Journal of the Chemical Society (Resumed) | pages=1342–1353 | url-access=subscription }}</ref><ref>{{cite journal | vauthors = Pertwee RG | title = Cannabinoid pharmacology: the first 66 years | journal = British Journal of Pharmacology | volume = 147 | issue = Suppl 1 | pages = S163–S171 | date = January 2006 | pmid = 16402100 | pmc = 1760722 | doi = 10.1038/sj.bjp.0706406 }}</ref> marking the first development of a [[cannabis extract]]. Its structure and chemical synthesis were achieved by 1940, followed by some of the first preclinical research studies to determine the effects of individual cannabis-derived compounds ''[[in vivo]]''.<ref name="Pertwee-2006">{{cite journal | vauthors = Pertwee RG | title = Cannabinoid pharmacology: the first 66 years | journal = British Journal of Pharmacology | volume = 147 | issue = Suppl 1 | pages = S163–S171 | date = January 2006 | pmid = 16402100 | pmc = 1760722 | doi = 10.1038/sj.bjp.0706406 }}</ref>