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Cellular differentiation
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=== Evolutionary perspectives on mechanisms === While [[evolution]]arily conserved molecular processes are involved in the cellular mechanisms underlying these switches, in animal species these are very different from the well-characterized [[operon|gene regulatory mechanisms]] of [[bacteria]], and even from those of the animals' closest [[holozoa|unicellular relatives]].<ref name="Newman">{{cite journal | vauthors = Newman SA | title = Cell differentiation: What have we learned in 50 years? | journal = Journal of Theoretical Biology | volume = 485 | pages = 110031 | date = January 2020 | pmid = 31568790 | doi = 10.1016/j.jtbi.2019.110031 | bibcode = 2020JThBi.48510031N | arxiv = 1907.09551 | doi-access = free }}</ref> Specifically, cell differentiation in animals is highly dependent on [[biomolecular condensate]]s of regulatory proteins and [[Enhancer (genetics)|enhancer]] DNA sequences.
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