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Chloroform
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===Solvent=== The [[hydrogen]] attached to [[carbon]] in chloroform participates in hydrogen bonding,<ref>{{cite journal|last1=Wiley |first1=G. R. |last2=Miller |first2=S. I. |doi=10.1021/ja00765a001|title=Thermodynamic parameters for hydrogen bonding of chloroform with Lewis bases in cyclohexane. Proton magnetic resonance study|year=1972|journal=Journal of the American Chemical Society|volume=94|issue=10|pages=3287β3293}}</ref><ref>{{cite journal|pmid=18855462|year=2008|last1=Kwak|first1=K.|last2=Rosenfeld|first2=D. E.|last3=Chung|first3=J. K.|last4=Fayer|first4=M. D.|title=Solute-solvent complex switching dynamics of chloroform between acetone and dimethylsulfoxide-two-dimensional IR chemical exchange spectroscopy|volume=112|issue=44|pages=13906β13915|doi=10.1021/jp806035w|pmc=2646412|journal=The Journal of Physical Chemistry B}}</ref> making it a good solvent for many materials. Worldwide, chloroform is also used in pesticide formulations, as a [[solvent]] for [[lipids]], [[rubber]], [[alkaloid]]s, [[wax]]es, [[gutta-percha]], and [[resin]]s, as a cleaning agent, as a grain [[fumigant]], in [[fire extinguishers]], and in the rubber industry.<ref name="cicad">{{citation | title=Chloroform | series=[[CICAD]] | volume=58 | publisher=[[World Health Organization]] | year=2004 | url=https://www.who.int/ipcs/publications/cicad/en/cicad58.pdf | url-status=live | archive-url=https://web.archive.org/web/20200731202031/https://www.who.int/ipcs/publications/cicad/en/cicad58.pdf | archive-date=31 July 2020}}</ref><ref name="pth">{{cite encyclopedia| editor1-last=Leikin |editor1-first=Jerrold B. | editor2-last=Paloucek |editor2-first=Frank P. | title=Chloroform | encyclopedia=Poisoning and Toxicology Handbook | edition=4th | publisher=Informa | year=2008 | page=774}}</ref> [[deuterated chloroform|{{chem2|CDCl3}}]] is a common solvent used in [[NMR spectroscopy]].<ref>{{cite journal|doi=10.1021/om100106e|title=NMR Chemical Shifts of Trace Impurities: Common Laboratory Solvents, Organics, and Gases in Deuterated Solvents Relevant to the Organometallic Chemist|journal=Organometallics|volume=29|issue=9|pages=2176β2179|year=2010|last1=Fulmer|first1=Gregory R.|last2=Miller|first2=Alexander J. M.|last3=Sherden|first3=Nathaniel H.|last4=Gottlieb|first4=Hugo E.|last5=Nudelman|first5=Abraham|last6=Stoltz|first6=Brian M.|last7=Bercaw|first7=John E.|last8=Goldberg|first8=Karen I.|s2cid=2755004 |url=https://authors.library.caltech.edu/18475/2/om100106e_si_001.pdf}}</ref>
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