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Diffuse axonal injury
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==History== The idea of DAI first came about as a result of studies by [[Sabina Strich]] on lesions of the white matter of individuals who had sustained head trauma years before.<ref name="Pearce"> {{cite journal | vauthors = Pearce JM | title = Observations on concussion. A review | journal = European Neurology | volume = 59 | issue = 3β4 | pages = 113β9 | year = 2007 | pmid = 18057896 | doi = 10.1159/000111872 | s2cid = 10245120 | url = https://www.karger.com/Article/PDF/000111872 | doi-access = free }} </ref> Strich first proposed the idea in 1956, calling it ''diffuse degeneration of white matter''; however, the more concise term "diffuse axonal injury" came to be preferred.<ref name="Gennarelli04"> {{cite book | vauthors = Gennarelli GA, Graham DI | chapter = Neuropathology | veditors = Silver JM, McAllister TW, Yudofsky SC | title = Textbook Of Traumatic Brain Injury | publisher = American Psychiatric Association | location = Washington, DC | year = 2005 | pages = 34 | isbn = 978-1-58562-105-7 | access-date = 2008-06-10 | chapter-url = https://books.google.com/books?id=3CuM6MviwMAC&q=neurotrauma&pg=PA47 }} </ref> Strich was researching the relationship between dementia and head trauma<ref name="Pearce"/> and asserted in 1956 that DAI played an integral role in the eventual development of dementia due to head trauma.<ref name="Hardman02"> {{cite journal | vauthors = Hardman JM, Manoukian A | title = Pathology of head trauma | journal = Neuroimaging Clinics of North America | volume = 12 | issue = 2 | pages = 175β87, vii | date = May 2002 | pmid = 12391630 | doi = 10.1016/S1052-5149(02)00009-6 }} </ref> The term DAI was introduced in the early 1980s.<ref name="Granacher07">{{cite book | vauthors = Granacher RP |title=Traumatic Brain Injury: Methods for Clinical & Forensic Neuropsychiatric Assessment, Second Edition |publisher=CRC |location=Boca Raton |year=2007 |pages= 26β32|isbn=978-0-8493-8138-6 |access-date=2008-07-06 |url= https://books.google.com/books?id=xt1YFydzXKQC&q=focal+diffuse+brain+injury+&pg=PA32}}</ref>
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