Editing Gallbladder (section)

===Inflammation===
{{Main|Cholecystitis}}
Known as [[cholecystitis]], inflammation of the gallbladder is commonly caused by obstruction of the duct with gallstones, which is known as [[cholelithiasis]]. Blocked bile accumulates, and pressure on the gallbladder wall may lead to the release of substances that cause inflammation, such as [[phospholipase]]. There is also the risk of bacterial infection. An inflamed gallbladder is likely to cause sharp and localised pain, fever, and tenderness in the upper, right corner of the abdomen, and may have a positive [[Murphy's sign]]. Cholecystitis is often managed with rest and antibiotics, particularly [[cephalosporin]]s and, in severe cases, [[metronidazole]]. Additionally the gallbladder may need to be removed surgically if inflammation has progressed far enough.<ref name=DAVIDSONS2010>{{cite book |editor=Nicki R. Colledge |editor2=Brian R. Walker |editor3=Stuart H. Ralston |title=Davidson's principles and practice of medicine|year=2010|publisher=Churchill Livingstone/Elsevier|location=Edinburgh|isbn=978-0-7020-3085-7|pages=977–984|edition=21st}}</ref>