Editing Microreactor (section)

===Analysis===
Microreactors can also enable experiments to be performed at a far lower scale and far higher experimental rates than currently possible in batch production, while not collecting the physical experimental output. The benefits here are primarily derived from the low operating scale, and the integration of the required sensor technologies to allow high quality understanding of an experiment. The integration of the required [[Chemical synthesis|synthesis]], purification and [[Analytical chemistry|analytical]] capabilities is impractical when operating outside of a microfluidic context.

====NMR====

Researchers at the Radboud University Nijmegen and Twente University, the Netherlands, have developed a microfluidic high-resolution NMR flow probe. They have shown a model reaction being followed in real-time. The combination of the uncompromised (sub-Hz) resolution and a low sample volume can prove to be a valuable tool for flow chemistry.<ref>{{cite journal |last1=Bart |first1=Jacob |last2=Kolkman |first2=Ard J. |last3=Oosthoek-de Vries |first3=Anna Jo |last4=Koch |first4=Kaspar |last5=Nieuwland |first5=Pieter J. |last6=Janssen |first6=Hans (J. W. G.) |last7=van Bentum |first7=Jan (P. J. M.) |last8=Ampt |first8=Kirsten A. M. |last9=Rutjes |first9=Floris P. J. T. |last10=Wijmenga |first10=Sybren S. |last11=Gardeniers |first11=Han (J. G. E.) |last12=Kentgens |first12=Arno P. M. |title=A Microfluidic High-Resolution NMR Flow Probe |journal=Journal of the American Chemical Society |date=15 April 2009 |volume=131 |issue=14 |pages=5014–5015 |doi=10.1021/ja900389x |pmid=19320484 |bibcode=2009JAChS.131.5014B |url=https://repository.ubn.ru.nl//bitstream/handle/2066/76115/76115.pdf }}</ref>

====Infrared spectroscopy====

Mettler Toledo and [[Bruker Optics]] offer dedicated equipment for monitoring, with [[attenuated total reflectance]] spectrometry (ATR spectrometry) in microreaction setups. The former has been demonstrated for reaction monitoring.<ref>{{cite journal |last1=Carter |first1=Catherine F. |last2=Lange |first2=Heiko |last3=Ley |first3=Steven V. |last4=Baxendale |first4=Ian R. |last5=Wittkamp |first5=Brian |last6=Goode |first6=Jon G. |last7=Gaunt |first7=Nigel L. |title=ReactIR Flow Cell: A New Analytical Tool for Continuous Flow Chemical Processing |journal=Organic Process Research & Development |date=19 March 2010 |volume=14 |issue=2 |pages=393–404 |doi=10.1021/op900305v }}</ref>  The latter has been successfully used for reaction monitoring<ref>{{cite journal |last1=Minnich |first1=Clemens B. |last2=Küpper |first2=Lukas |last3=Liauw |first3=Marcel A. |last4=Greiner |first4=Lasse |title=Combining reaction calorimetry and ATR-IR spectroscopy for the operando monitoring of ionic liquids synthesis |journal=Catalysis Today |date=August 2007 |volume=126 |issue=1–2 |pages=191–195 |doi=10.1016/j.cattod.2006.12.007 }}</ref>  and determining dispersion characteristics<ref>{{cite journal |last1=Minnich |first1=Clemens B. |last2=Sipeer |first2=Frank |last3=Greiner |first3=Lasse |last4=Liauw |first4=Marcel A. |title=Determination of the Dispersion Characteristics of Miniaturized Coiled Reactors with Fiber-Optic Fourier Transform Mid-infrared Spectroscopy |journal=Industrial & Engineering Chemistry Research |date=16 June 2010 |volume=49 |issue=12 |pages=5530–5535 |doi=10.1021/ie901094q }}</ref>  of a microreactor.