Editing Monoamine transporter (section)

===Attention deficit hyperactivity disorder===
It has been observed that the hyperactivity, inattention, and impulsivity in ADHD is related to abnormal DAT function and regulation.  [[Dopaminergic]] hypofunction in the frontal cortex and [[basal ganglia]] is a neurobiological feature observed in ADHD.<ref name=Fone/>  [[Psychostimulants]] that potently inhibit DAT, such as [[methylphenidate]] and [[amphetamine]], are efficacious in treating ADHD.  Methylphenidate (Ritalin) inhibits both DAT and NET, which results in an increase in extracellular dopamine and norepinephrine that can readily bind postsynaptic cells.  Methylphenidate targets DAT as a [[Reuptake inhibitor|non-selective reuptake inhibitor]].<ref name=rama/>   Methylphenidate is not an inhibitor of SERT.<ref name=Fone>{{cite journal|doi=10.1016/j.coph.2004.10.001|last=Fone|first=Kevin|author2=David J Nutt|title=Stimulants: use and abuse in the treatment of attention deficit hyperactivity disorder|journal=Current Opinion in Pharmacology|date=February 2005|volume=5|issue=1|pages=87–93|pmid=15661631}}</ref>