Editing Multiple system atrophy (section)

=== Radiologic ===

[[File:Hot cross bun sign.jpg|alt=An MRI finding that is seen commonly in Multiple System atrophy. This occurs on the Pons.|thumb|upright=.9|The "Hot Cross Bun" sign, found in MSA with MRI]]
Both MRI and CT scanning may show a decrease in the size of the cerebellum and pons in those with cerebellar features (MSA-C). The putamen is hypointense on T2-weighted MRI and may show an increased deposition of iron in the Parkinsonian (MSA-P) form. In MSA-C, a "hot cross bun" sign is sometimes found; it reflects atrophy of the pontocerebellar tracts that give T2 hyper intense signal intensity in the atrophic pons.

MRI changes are not required to diagnose the disease as these features are often absent, especially early in the course of the disease. Additionally, the changes can be quite subtle and  are usually missed by examiners who are not experienced with MSA.{{citation needed|date=December 2020}}