Editing Nuclear Overhauser effect (section)

== Examples of nuclear Overhauser effect ==
[[File:NOE in action.jpg|thumb|upright=1.3|Nuclear Overhauser effect<ref name=":0">{{Cite journal|last=M. Kazem-Rostami, N. G. Akhmedov and S. Faramarzi|date=2019|title=Molecular lambda shape light-driven dual switches: spectroscopic and computational studies of the photoisomerization of bisazo Tröger base analogs|journal=Journal of Molecular Structure|volume=1178|pages=538–543|doi=10.1016/j.molstruc.2018.10.071|bibcode=2019JMoSt1178..538K |s2cid=105312344 }}</ref>]]
The figure (top) displays how Nuclear Overhauser Effect Spectroscopy can elucidate the structure of a switchable compound. In this example,<ref name=":0" /> the proton designated as {H} shows two different sets of NOEs depending on the [[isomerization]] state (''cis'' or ''trans'') of the switchable [[Azo compound|azo]] groups. In the ''trans'' state proton {H} is far from the [[phenyl group]] showing blue coloured NOEs; while the ''cis'' state holds proton {H} in the vicinity of the phenyl group resulting in the emergence of new NOEs (show in red).

Another example (bottom) where application where the NOE is useful to assign resonances and determine configuration is polysaccharides. For instance, complex glucans possess a multitude of overlapping signals, especially in a proton spectrum. Therefore, it is advantageous to utilize 2D NMR experiments including NOESY for the assignment of signals. See, for example, [[Nuclear magnetic resonance spectroscopy of carbohydrates#Application of various NMR techniques to carbohydrates|NOE of carbohydrates]].
[[File:Homonuclear correlations in saccharides.jpg|thumb|left|upright=1.5|Homonuclear NMR techniques in carbohydrate studies.]]{{clear}}