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Probabilistic context-free grammar
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====Implementations==== RNA secondary structure implementations based on PCFG approaches can be utilized in : * Finding consensus structure by optimizing structure joint probabilities over MSA.<ref name="Knudsen 2003" /><ref name="Knudsen 1999" /> * Modeling base-pair covariation to detecting homology in database searches.<ref name="Eddy 1994" /> * pairwise simultaneous folding and alignment.<ref name="Rivas 2001" /><ref name="Holmes 2002" /> Different implementation of these approaches exist. For example, Pfold is used in secondary structure prediction from a group of related RNA sequences,<ref name="Knudsen 2003" /> covariance models are used in searching databases for homologous sequences and RNA annotation and classification,<ref name="Eddy 1994" /><ref name="Gardner 2010" /> RNApromo, CMFinder and TEISER are used in finding stable structural motifs in RNAs.<ref name="Yao 2006" /><ref name="Rabani 2008" /><ref name="Goodarzi 2012" />
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