Editing Quinone (section)

=== Medical ===
Several quinones are of pharmacological interest.  They form a major class of anticancer cytotoxins.  One example is [[daunorubicin]], which is antileukemic.<ref name=Obrien/> Some of them show anti-[[tumor]]al activity. They embody some claims in [[herbal medicine]]. These applications include purgative ([[sennosides]]), antimicrobial and antiparasitic ([[rhein (molecule)|rhein]] and [[saprorthoquinone]], [[atovaquone]]), anti-tumor ([[emodin]] and [[juglone]]), inhibition of [[PGE2]] biosynthesis ([[arnebinone]] and [[arnebifuranone]]) and anti-[[cardiovascular disease]] ([[Salvia miltiorrhiza|tanshinone]]).<ref>Liu H., "Extraction and Isolation of Compounds from Herbal Medicines" in 'Traditional Herbal Medicine Research Methods', ed by Willow JH Liu 2011 John Wiley and Sons, Inc.</ref>  [[Malbranchea cinnamomea]] is a thermophilic fungus, which produces a quinone antibiotic.

Another quinone-containing drug is [[Mecarbinate]] ([[dimecarbine]]), made by the reaction of ethyl [[N-methyl-β-aminocrotonate]] with para-benzoquinone. Others include [[Amendol]], [[Oxyphemedol]], [[Phemedol]] all in FR5142 (M) ― 1967-06-05.{{clarify|date=July 2018}} Note: These are all indoles made via the [[Nenitzescu indole synthesis]]. The antineoplastic [[Apaziquone]].

Benzoquinone compounds are a metabolite of [[paracetamol]].<ref>{{Cite journal
 | doi = 10.1073/pnas.81.5.1327
 | last1 = Dahlin | first1 = D. C.
 | last2 = Miwa | first2 = G. T.
 | last3 = Lu | first3 = A. Y.
 | last4 = Nelson | first4 = S. D.
 | title = N-acetyl-p-benzoquinone imine: a cytochrome P-450-mediated oxidation product of acetaminophen
 | journal = Proceedings of the National Academy of Sciences of the United States of America
 | volume = 81
 | issue = 5
 | pages = 1327–1331
 | year = 1984
 | pmid = 6424115
 | pmc = 344826
| bibcode = 1984PNAS...81.1327D | doi-access = free }}</ref>