Editing Recombinant DNA (section)

===Recombinant blood clotting factor VIII===
It is the recombinant form of [[factor VIII]], a blood-clotting protein that is administered to patients with the bleeding disorder [[hemophilia]], who are unable to produce factor VIII in quantities sufficient to support normal blood coagulation.<ref name="pmid|21056743">{{Cite journal
 | last1 = Manco-Johnson | first1 = M. J.
 | doi = 10.1016/j.yapd.2010.08.007
 | title = Advances in the Care and Treatment of Children with Hemophilia
 | journal = Advances in Pediatrics
 | volume = 57
 | issue = 1
 | pages = 287–294
 | year = 2010
 | pmid = 21056743
}}</ref> Before the development of recombinant factor VIII, the protein was obtained by processing large quantities of human blood from multiple donors, which carried a very high risk of transmission of [[Blood-borne disease|blood borne infectious diseases]], for example HIV and hepatitis B.