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Synovial fluid
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=== Chemistry === The mucin clot test is a very old approach to determining if an inflammatory infiltrate is present. In this test, acetic acid is added to the synovial fluid specimen. In a normal specimen, this should lead to a congealing of the hyaluronic acid, forming a 'mucin clot.' If inflammation is present, a mucin clot is not formed (the hyaluronic acid is degraded).<ref name=demais2009>{{Citation |last=De Mais |first=Daniel |year=2009 |title=Quick Compendium of Clinical Pathology |edition=2nd |publisher=[[ASCP Press]] |location=Chicago |isbn=9780891895671 |oclc=692198047 |url-access=registration |url=https://archive.org/details/quickcompendiumo0000mais }}{{pages needed|date=April 2013}}</ref> Lactate is elevated in septic arthritis, usually above 250 mg/dL. Complement factors are decreased in rheumatoid arthritis and lupus arthritis.
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