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X-inactivation
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===Chromosomal component=== The X-inactivation center (or simply XIC) on the X chromosome is [[necessary and sufficient]] to cause X-inactivation. [[Chromosomal translocation]]s which place the XIC on an autosome lead to inactivation of the autosome, and X chromosomes lacking the XIC are not inactivated.<ref name=":6" /><ref name=":7" /> The XIC contains four non-[[translation (genetics)|translated]] [[RNA]] genes, [[Xist]], [[Xist#Tsix antisense transcript|Tsix]], [[Jpx (gene)|Jpx]] and [[Ftx (gene)|Ftx]], which are involved in X-inactivation. The XIC also contains binding sites for both known and unknown [[regulatory protein]]s.<ref name=":8" />
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