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Anxiolytic
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=== Antiepileptics === Antiepileptics are rarely prescribed as an off-label treatment for anxiety disorders and post-traumatic stress disorders.<ref>{{Cite web |date=2014-10-28 |title=What is the Best Anticonvulsant for Anxiety? |url=https://psychcentral.com/anxiety/antipsychotics-anticonvulsants-for-anxiety-disorders |access-date=2023-10-19 |website=Psych Central |language=en}}</ref> There have been some suggestions that they may help with anxiety symptoms but there is generally a lack of research on its use.<ref name="Garakani 2020">{{Cite journal |last1=Garakani |first1=Amir |last2=Murrough |first2=James W. |last3=Freire |first3=Rafael C. |last4=Thom |first4=Robyn P. |last5=Larkin |first5=Kaitlyn |last6=Buono |first6=Frank D. |last7=Iosifescu |first7=Dan V. |date=2020 |title=Pharmacotherapy of Anxiety Disorders: Current and Emerging Treatment Options |journal=Frontiers in Psychiatry |volume=11 |doi= 10.3389/fpsyt.2020.595584|doi-access=free |pmid=33424664 |pmc=7786299 |issn=1664-0640}}</ref> One antiepileptic, [[pregabalin]], has been found to be better at treating GAD than a placebo, and comparable effects to benzodiazepines. It has also been shown be potentially efficient in treating social anxiety disorder. [[Gabapentin]] has been prescribed off-label for anxiety despite a lack of research evidence supporting such use, although some studies have indicated that it may relieve anxiety symptoms. The potential anxiolytic effect of [[tiagabine]] has been observed in some pre-clinical trials, but its effectiveness has not yet been proved. Similarly, there is a lack of research on [[valproate]] for the treatment of anxiety disorders.<ref name="Garakani 2020" />
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