Editing Argument from poor design (section)

===Responses to counterarguments===
In response to the claim that uses have been found for "junk" DNA, proponents note that the fact that some [[non-coding DNA]] has a purpose does not establish that all non-coding DNA has a purpose, and that the human genome does include [[pseudogenes]] that are nonfunctional "junk", with others noting that some sections of DNA can be randomized, cut, or added to with no apparent effect on the organism in question.<ref>{{cite web |first=Mark |last=Isaak |year=2004 |url=http://www.talkorigins.org/indexcc/CB/CB130.html |title=Claim CB130 |publisher=Talk.Origins |url-status=live |archive-url=https://web.archive.org/web/20060911070043/http://www.talkorigins.org/indexcc/CB/CB130.html |archive-date=2006-09-11 }}</ref> The original study that suggested that the ''Makorin1-p1'' served some purpose<ref>{{cite journal | last1 = Hirotsune | first1 = S | last2 = Yoshida | first2 = N | last3 = Chen | first3 = A | last4 = Garrett | first4 = L | last5 = Sugiyama | first5 = F | last6 = Takahashi | first6 = S | last7 = Yagami | first7 = K | last8 = Wynshaw-Boris | first8 = A | last9 = Yoshiki | first9 = A. | year = 2003 | title = An expressed pseudogene regulates the messenger-RNA stability of its homologous coding gene | journal = Nature | volume = 423 | issue = 6935 | pages = 91–6 | doi = 10.1038/nature01535 | pmid = 12721631 | display-authors = etal | bibcode = 2003Natur.423...91H | s2cid = 4360619 }}</ref> has been disputed.<ref>{{cite journal | last1 = Gray | first1 = TA | last2 = Wilson | first2 = A | last3 = Fortin | first3 = PJ | last4 = Nicholls | first4 = RD | year = 2006 | title = The putatively functional Mkrn1-p1 pseudogene is neither expressed nor imprinted, nor does it regulate its source gene in trans | journal = Proc Natl Acad Sci USA | volume = 103 | issue = 32 | pages = 12039–12044 | doi = 10.1073/pnas.0602216103 | pmid = 16882727 | pmc = 1567693 | bibcode = 2006PNAS..10312039G | doi-access = free }}</ref> However, the original study is still frequently cited in newer studies and articles on pseudogenes previously thought to be nonfunctional.<ref>{{cite web|url=https://scholar.google.com/scholar?oe=utf-8&um=1&ie=UTF-8&lr&cites=16337157008352528383|title=Google Scholar|website=scholar.google.com}}</ref>