Editing Bioavailability (section)

== Notes ==
{{cnote|TH|One of the few exceptions where a drug shows ''F'' of over 100% is [[theophylline]]. If administered as an oral solution ''F'' is 111%, since the drug is completely absorbed and first-pass metabolism in the lung after intravenous administration is bypassed.<ref name='Schuppan1981'>{{cite journal |pmid=7251238 |year=1981 |last1=Schuppan |first1=D. |last2=Molz |first2=K. H. |last3=Staib |first3=A. H. |last4=Rietbrock |first4=N. |title=Bioavailability of theophylline from a sustained-release aminophylline formulation (Euphyllin retard tablets) – plasma levels after single and multiple oral doses |volume=19 |issue=5 |pages=223–227 |journal=International Journal of Clinical Pharmacology, Therapy, and Toxicology}}</ref>}}
{{cnote|OB|Reference listed drug products (i.e., innovator's) as well as [[generic drug]] products that have been approved based on an [[Abbreviated New Drug Application]]  are given in FDA's ''[[Approved Drug Products with Therapeutic Equivalence Evaluations|Orange Book]]''.
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