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Biomolecule
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====Apoenzymes==== An [[apoenzyme]] (or, generally, an apoprotein) is the protein without any small-molecule cofactors, substrates, or inhibitors bound. It is often important as an inactive storage, transport, or secretory form of a protein. This is required, for instance, to protect the secretory cell from the activity of that protein. Apoenzymes become active enzymes on addition of a [[cofactor (biochemistry)|cofactor]]. Cofactors can be either inorganic (e.g., metal ions and [[iron-sulfur clusters]]) or organic compounds, (e.g., [Flavin group|flavin] and [[heme]]). Organic cofactors can be either [[prosthetic groups]], which are tightly bound to an enzyme, or [[coenzymes]], which are released from the enzyme's active site during the reaction.
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