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Chloroform
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===Refrigerant=== Chloroform is used as a precursor to make R-22 (chlorodifluoromethane). This is done by reacting it with a solution of [[hydrofluoric acid]] (HF) which fluorinates the {{chem2|CHCl3}} molecule and releases hydrochloric acid as a byproduct.<ref>{{cite web | url=https://www.ebi.ac.uk/chebi/es/searchId.do?printerFriendlyView=true&locale=null&chebiId=35255&viewTermLineage=null&structureView=&|title=Chloroform (CHEBI:35255)}}</ref> Before the [[Montreal Protocol]] was enforced, most of the chloroform produced in the United States was used in the production of [[chlorodifluoromethane]]. However, its production remains high, as it is a key precursor of PTFE.<ref>{{cite web|url=https://www.atsdr.cdc.gov/ToxProfiles/tp6-c4.pdf|title=Production, import/export, use, and disposal|access-date=5 April 2023|website=atsdr.cdc.gov}}</ref> Although chloroform has properties such as a low boiling point, and a low global warming potential of only 31 (compared to the 1760 of R-22), which are appealing properties for a refrigerant, there is little information to suggest that it has seen widespread use as a refrigerant in any consumer products.<ref>{{cite encyclopedia| title=Chloroform as a pollutant |encyclopedia=The Encyclopedia of World Problems | url=http://encyclopedia.uia.org/en/problem/chloroform-pollutant#:~:text=Most%20chloroform%20is%20manufactured%20to,spot%20removers%2C%20and%20various%20solvents}}</ref>
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