Editing DNA microarray (section)

=== Standardization ===
Microarray data is difficult to exchange due to the lack of standardization in platform fabrication, assay protocols, and analysis methods. This presents an [[interoperability]] problem in [[bioinformatics]]. Various [[grass-roots]] [[open-source model|open-source]] projects are trying to ease the exchange and analysis of data produced with non-proprietary chips:

For example, the "Minimum Information About a Microarray Experiment" ([[MIAME]]) checklist helps define the level of detail that should exist and is being adopted by many [[Scientific journal|journals]] as a requirement for the submission of papers incorporating microarray results. But MIAME does not describe the format for the information, so while many formats can support the MIAME requirements, {{as of|lc=y|2007}} no format permits verification of complete semantic compliance. The "MicroArray Quality Control (MAQC) Project" is being conducted by the US [[Food and Drug Administration]] (FDA) to develop standards and quality control metrics which will eventually allow the use of MicroArray data in drug discovery, clinical practice and regulatory decision-making.<ref>[https://web.archive.org/web/20051208055601/http://www.fda.gov/nctr/science/centers/toxicoinformatics/maqc/ NCTR Center for Toxicoinformatics – MAQC Project<!-- Bot generated title -->]</ref> The [[MGED Society]] has developed standards for the representation of gene expression experiment results and relevant annotations.