Editing DNA synthesis (section)

===Base pair synthesis===
It has been reported that new [[nucleobase]] pairs can be synthesized, as well as A-T ([[adenine]] - [[thymine]]) and G-C ([[guanine]] - [[cytosine]]). Synthetic nucleotides can be used to expand the genetic alphabet and allow specific modification of DNA sites. Even just a third base pair would expand the number of amino acids that can be encoded by DNA from the existing 20 amino acids to a possible 172.<ref name="Fikes">{{cite news|url=http://www.utsandiego.com/news/2014/may/08/tp-life-engineered-with-expanded-genetic-code/ |title=Life engineered with expanded genetic code |last=Fikes |first=Bradley J. |date=May 8, 2014 |work=San Diego Union Tribune |access-date=8 May 2014 |url-status=dead |archive-url=https://web.archive.org/web/20140509001048/http://www.utsandiego.com/news/2014/may/08/tp-life-engineered-with-expanded-genetic-code/ |archive-date=9 May 2014 }}</ref> 
[[Hachimoji DNA]] is built from eight nucleotide letters, forming four possible base pairs. It therefore doubles the information density of natural DNA. In studies, RNA has even been produced from hachimoji DNA. This technology could also be used to allow data storage in DNA.<ref>{{cite journal |last1=Hoshika |first1=Shuichi |title=Hachimoji DNA and RNA. A Genetic System with Eight Building Blocks |journal=Science |date=2020 |volume=363 |issue=6429 |pages=884–887 |doi=10.1126/science.aat0971 |pmid=30792304|pmc=6413494 }}</ref>