Editing GC-content (section)

=== Systematics  ===
The [[species problem]] in non-eukaryotic taxonomy has led to various suggestions in classifying bacteria, and the ''ad hoc committee on reconciliation of approaches to bacterial systematics'' of 1987 has recommended use of GC-ratios in higher-level hierarchical classification.<ref>{{cite journal |doi=10.1099/00207713-37-4-463 |author=Wayne LG |title=Report of the ad hoc committee on reconciliation of approaches to bacterial systematic |journal=International Journal of Systematic Bacteriology |volume=37 |issue=4 |pages=463–4 |year=1987|display-authors=etal|doi-access=free }}</ref> For example, the [[Actinomycetota]] are characterised as "high GC-content [[bacterium|bacteria]]".<ref>[https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Tree&id=1760&lvl=3&lin=f&keep=1&srchmode=1&unlock Taxonomy browser on NCBI]</ref> In ''[[Streptomyces coelicolor]]'' A3(2), GC-content is 72%.<ref>[https://www.ncbi.nlm.nih.gov/sites/entrez?db=genomeprj&cmd=Retrieve&dopt=Overview&list_uids=242 Whole genome data of ''Streptomyces coelicolor'' A3(2) on NCBI]</ref> With the use of more reliable, modern methods of molecular systematics, the GC-content definition of Actinomycetota has been abolished and low-GC bacteria of this [[clade]] have been found.<ref name="lowGCActinoacteria">{{cite journal |vauthors=Ghai R, McMahon KD, Rodriguez-Valera F |title=Breaking a paradigm: Cosmopolitan and abundant freshwater actinobacteria are low GC |journal=Environmental Microbiology Reports |volume=4 |issue=1 |pages=29–35 |year=2012 |doi=10.1111/j.1758-2229.2011.00274.x |pmid=23757226|bibcode=2012EnvMR...4...29G }}</ref>