Editing Malignant transformation (section)

==== ''Helicobacter pylori'' and gastric cancer====

In 1995 epidemiologic evidence indicated that ''Helicobacter pylori'' infection increases the risk for gastric carcinoma.<ref name="pmid7762738">{{cite journal |vauthors=Correa P |title=Helicobacter pylori and gastric carcinogenesis |journal=Am. J. Surg. Pathol. |volume=19 |pages=S37–43 |year=1995 |issue=Suppl 1 |pmid=7762738 }}</ref>  More recently, experimental evidence showed that infection with ''[[Helicobacter pylori]]'' cagA-positive bacterial strains results in severe degrees of inflammation and oxidative DNA damage, leading to progression to gastric cancer.<ref name="pmid24664859">{{cite journal |vauthors=Raza Y, Khan A, Farooqui A, Mubarak M, Facista A, Akhtar SS, Khan S, Kazi JI, Bernstein C, Kazmi SU |title=Oxidative DNA damage as a potential early biomarker of Helicobacter pylori associated carcinogenesis |journal=Pathol. Oncol. Res. |volume=20 |issue=4 |pages=839–46 |year=2014 |pmid=24664859 |doi=10.1007/s12253-014-9762-1 |s2cid=18727504 }}</ref>