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Nucleic acid sequence
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=== Sequence motifs === {{Main|Sequence motif}} Frequently the primary structure encodes motifs that are of functional importance. Some examples of sequence motifs are: the C/D<!-- --><ref>{{Cite journal |last=Samarsky |first=DA |last2=Fournier MJ |last3=Singer RH |last4=Bertrand E |year=1998 |title=The snoRNA box C/D motif directs nucleolar targeting and also couples snoRNA synthesis and localization |journal=The EMBO Journal |volume=17 |issue=13 |pages=3747–57 |doi=10.1093/emboj/17.13.3747 |pmc=1170710 |pmid=9649444}}</ref> and H/ACA boxes<!-- --><ref>{{Cite journal |last=Ganot |first=Philippe |last2=Caizergues-Ferrer |first2=Michèle |last3=Kiss |first3=Tamás |date=1 April 1997 |title=The family of box ACA small nucleolar RNAs is defined by an evolutionarily conserved secondary structure and ubiquitous sequence elements essential for RNA accumulation |journal=[[Genes & Development]] |volume=11 |issue=7 |pages=941–56 |doi=10.1101/gad.11.7.941 |pmid=9106664 |doi-access=free}}</ref> of [[snoRNA]]s, [[LSm|Sm binding site]] found in spliceosomal RNAs such as [[U1 spliceosomal RNA|U1]], [[U2 spliceosomal RNA|U2]], [[U4 spliceosomal RNA|U4]], [[U5 spliceosomal RNA|U5]], [[U6 spliceosomal RNA|U6]], [[U12 minor spliceosomal RNA|U12]] and [[Small nucleolar RNA U3|U3]], the [[Shine-Dalgarno sequence]],<!-- --><ref>{{Cite journal |last=Shine J, Dalgarno L |author-link=John Shine |author-link2=Lynn Dalgarno |year=1975 |title=Determinant of cistron specificity in bacterial ribosomes |journal=Nature |volume=254 |issue=5495 |pages=34–38 |bibcode=1975Natur.254...34S |doi=10.1038/254034a0 |pmid=803646 |s2cid=4162567}}</ref> the [[Kozak consensus sequence]]<!-- --><ref name="Kozak1987">{{Cite journal |last=Kozak M |date=October 1987 |title=An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs |journal=Nucleic Acids Res. |volume=15 |issue=20 |pages=8125–48 |doi=10.1093/nar/15.20.8125 |pmc=306349 |pmid=3313277}}</ref> and the [[RNA polymerase III|RNA polymerase III terminator]]<!-- -->.<ref name="pmid6263489">{{Cite journal |last=Bogenhagen DF, Brown DD |year=1981 |title=Nucleotide sequences in Xenopus 5S DNA required for transcription termination. |journal=Cell |volume=24 |issue=1 |pages=261–70 |doi=10.1016/0092-8674(81)90522-5 |pmid=6263489 |s2cid=9982829}}</ref>
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