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Persistent organic pollutant
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=== Reproductive system === The same study in 2002<ref name="Damstra, T. 2002"/> with evidence of a link from POPs to [[endocrine disruptor|endocrine disruption]] also linked low dose exposure of POPs to [[reproductive health]] effects. The study stated that POP exposure can lead to negative health effects especially in the [[human male reproductive system|male reproductive system]], such as decreased [[sperm]] quality and quantity, altered sex ratio and early [[puberty]] onset. For females exposed to POPs, altered [[human female reproductive system|reproductive tissues]] and [[pregnancy]] outcomes as well as [[endometriosis]] have been reported.<ref name="El-Shahawi, M.S. 2010"/> ====Gestational weight gain and newborn head circumference==== A Greek study from 2014 investigated the link between maternal weight gain during pregnancy, their [[polychlorinated biphenyl|PCB]]-exposure level and PCB level in their newborn infants, their [[birth weight]], [[Gestational age (obstetrics)|gestational age]], and head circumference. The lower the birth weight and head circumference of the infants was, the higher POP levels during [[prenatal development]] had been, but only if mothers had either excessive or inadequate weight gain during pregnancy. No correlation between POP exposure and gestational age was found.<ref>{{cite journal|last=Vafeiadi|first=M|author2=Vrijheid M |author3=Fthenou E |author4=Chalkiadaki G |author5=Rantakokko P |author6=Kiviranta H |author7=Kyrtopoulos SA |author8=Chatzi L |author9=Kogevinas M |title=Persistent organic pollutants exposure during pregnancy, maternal gestational weight gain, and birth outcomes in the mother-child cohort in Crete, Greece (RHEA study)|journal=Environ. Int.|year=2014|volume=64|pages=116β123|doi=10.1016/j.envint.2013.12.015|pmid=24389008|doi-access=free|bibcode=2014EnInt..64..116V}}</ref> A 2013 [[case-control study]] conducted 2009 in Indian mothers and their offspring showed prenatal exposure of two types of [[organochlorine pesticides]] ([[Hexachlorocyclohexane|HCH]], [[DDT]] and [[Dichlorodiphenyldichloroethylene|DDE]]) impaired the growth of the [[fetus]], reduced the birth weight, length, head circumference and chest circumference.<ref>{{cite journal|last=Dewan|first=Jain V|author2=Gupta P |author3=Banerjee BD. |title=Organochlorine pesticide residues in maternal blood, cord blood, placenta, and breastmilk and their relation to birth size|journal=Chemosphere|date=February 2013|volume=90|issue=5|pages=1704β1710|doi= 10.1016/j.chemosphere.2012.09.083|pmid=23141556|bibcode=2013Chmsp..90.1704D}}</ref><ref>{{cite journal | author = Damstra T | year = 2002 | title = Potential Effects of Certain Persistent Organic Pollutants and Endocrine Disrupting Chemicals on Health of Children | journal = Clinical Toxicology | volume = 40 | issue = 4| pages = 457β465 | pmid = 12216998 | doi = 10.1081/clt-120006748 | s2cid = 23550634 }}</ref>
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