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Procainamide
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==Chemistry== 4-amino-N-2-(diethylamino)ethyl-benzamide (also known as [[Diethylethanolamine|para-amino-N-2-(diethylamino)ethyl-benzamide]] because the amino substituent is attached to the para-position, [[Arene substitution patterns]] of the [[benzene ring]]) is a synthetic [[organic compound]] with the chemical formula C13-H21-N3-O.<ref name="Drug">{{cite web |date=27 June 2018 |title=Procainamide |url=http://www.drugbank.ca/drugs/DB01035 |website=www.drugbank.ca |access-date=28 June 2018}}</ref> Procainamide is structurally similar to [[procaine]], but in place of an ester group, procainamide contains an amide group. This substitution is the reason why procainamide exhibits a longer half-life time than procaine.<ref>{{cite book | vauthors = Adams HR |year=1995 |title=Drugs Acting on the Cardiovascular System. Veterinary Pharmacology and Therapeutics |edition=7th |pages=451β500}}</ref><ref>{{cite book | vauthors = Plumb DC |year=1999 |title=Veterinary Drug Handbook |publisher=PharmaVet Publishing |location=White Bear Lake, USA}}</ref> Procainamide belongs to the [[benzamides|aminobenzamides]]. These are [[aromatic]] [[carboxylic acid]] derivatives consisting of an amide with a [[benzamide]] moiety and a [[triethylamine]] attached to the [[amide]] [[nitrogen]].<ref name="Drug"/><ref>{{cite web |author=EBI Web Team |title=CHEBI:8428 - procainamide |url=http://www.ebi.ac.uk/chebi/searchFreeText.do?searchString=51-06-9 |website=www.ebi.ac.uk |access-date=28 June 2018}}</ref><ref>{{cite book | vauthors = DeRuiter J |year=2005 |chapter=Amides and Related Functional Groups |title=Principles of Drug Action |page=1}}</ref> In certain lines, the ''para''-amino group might become a target site to attach further paraphernalia, e.g. ''ref.'' Ex18 in {{US patent|7115750}}.
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