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Pyruvate dehydrogenase complex
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=== Dihydrolipoyl transacetylase (E2) === At this point, the lipoate-thioester functionality is translocated into the [[Dihydrolipoyl transacetylase]] (E2) active site,<ref name=":0" /> where a transacylation reaction transfers the acetyl from the "swinging arm" of lipoyl to the thiol of [[coenzyme A]]. This produces [[acetyl-CoA]], which is released from the enzyme complex and subsequently enters the [[citric acid cycle]]. E2 can also be known as lipoamide reductase-transacetylase.
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