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Xeroderma pigmentosum
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== Culture and society== Because people with XP need to strictly avoid sunlight, but can go outside at night, they have been called ''children of the dark'', ''children of the night'', and ''vampire children''. These terms can be considered derogatory.<ref>{{Cite book |last=Almeida |first=Craig A. |url=https://books.google.com/books?id=j0RV27loexoC&pg=PT306 |title=Cancer: Basic Science and Clinical Aspects |last2=Barry |first2=Sheila A. |date=2011-08-26 |publisher=John Wiley & Sons |isbn=9781444357394 |language=en}}</ref> XP has been a plot element in several fictional works. One of the common themes in films about XP is whether teens with XP will risk sun exposure in pursuit of a romantic partner.<ref>{{Cite news |last=Walsh |first=Katie |date=23 March 2018 |title=No spark in sick teen romance - Baltimore Sun |url=http://digitaledition.baltimoresun.com/tribune/article_popover.aspx?guid=7ae2bd5e-6b2d-405b-b7b2-baa51b206f34 |access-date=2018-07-08 |work=Baltimore Sun |agency=Tribune New Service}}</ref> Film series like ''[[Children of Darkness (1921 film)|Children of Darkness]]'', a German silent-drama film which was released in two parts in the year of 1921 and 1922 respectively, were among some of the initially popular movies that were made about XP.{{cn|date=October 2024}} Other films, like the 1964 American [[Drama (film and television)|drama film]] ''[[Della (film)|Della]]'', starring [[Joan Crawford]], [[Paul Burke (actor)|Paul Burke]], [[Charles Bickford]] and [[Diane Baker]], directed by [[Robert Gist]], which was originally produced by [[Four Star Television]] as a [[television pilot]] for a proposed [[NBC]] series named ''Royal Bay'', was also based on this [[skin disease]].{{cn|date=October 2024}} ''[[The Dark Side of the Sun (film)|The Dark Side of the Sun]]'', a 1988 American-Yugoslavian [[drama film]], was directed by Božidar Nikolić and stars [[Brad Pitt]] for his first ever leading role as a young man in search of a cure for his disorder.{{cn|date=October 2024}} ''[[The Others (2001 film)|The Others]]'', a 2001 American [[psychological horror]] film starring [[Nicole Kidman]], features two children, Anne and Nicholas, who must avoid all sunlight because of a rare disease characterized by [[photosensitivity]].{{cn|date=October 2024}} A [[CBS]] [[television movie]] aired in 1994, ''Children of the Dark'', was based on the story of the real-life couple Jim and Kim Harrison, whose two daughters have XP.<ref>{{Cite web |last=Holder |first=Kathleen |name-list-style=vanc |date=1994-05-01 |title=Family in Twilight for Sun-Sensitive Girls : Health: Two daughters have a rare genetic intolerance that leaves victims vulnerable to skin cancers, blindness and neurological damage after exposure to sunlight |url=https://www.latimes.com/archives/la-xpm-1994-05-01-me-52495-story.html |access-date=2017-09-14 |publisher=[[Associated Press]]}}</ref><ref>{{Cite web |last=Voros |first=Drew |name-list-style=vanc |date=1994-04-15 |title=Review: 'Children of the Dark' |url=https://variety.com/1994/tv/reviews/children-of-the-dark-1200436702/ |access-date=2017-09-14 |publisher=[[Variety (magazine)|Variety]]}}</ref> [[Lurlene McDaniel]]'s [[young adult book]] ''How I Do Love Thee'' features the story "Night Vision", in which the protagonist, [[leukemia]] survivor Brett, falls in love with a girl named Shayla that has XP.{{cn|date=October 2024}} Christopher Snow, the protagonist of novelist [[Dean Koontz|Dean Koontz's]] ''[[Moonlight Bay Trilogy]]'', has XP and therefore must live most of his life during the night. The first two entries of the trilogy, ''[[Fear Nothing]]'' and ''[[Seize the Night (novel)|Seize the Night]]'', were both published in 1998. The final entry in the trilogy, tentatively titled ''[[Ride the Storm (novel)|Ride the Storm]]'', has yet to be published as of August 2020.<ref name="2018 Interview">[http://www.capradio.org/blogs/between-the-lines/2017/12/08/dean-koontz-takes-readers-on-a-techno-thriller-ride-in-his-new-jane-hawk-series 2017 Interview], capradio.org, 2017.</ref><ref>{{Cite web |title=Frequently Asked Questions |url=http://www.deankoontz.com/faq-categories/general-faq |url-status=dead |archive-url=https://web.archive.org/web/20180824135156/http://www.deankoontz.com/faq-categories/general-faq |archive-date=24 August 2018 |access-date=24 August 2018 |website=Dean Koontz}}</ref> The 2011 [[France|French]] [[Drama (film and television)|drama film]] ''The Moon Child'' is based on a 13-year-old child with XP, which prevents him from exposing himself to daylight. The 2012 documentary ''Sun Kissed'' explores the XP problem on the Navajo Indian Reservation, and links it to the [[Founder effect|genetic legacy]] of the [[Long Walk of the Navajo]], when the Navajo people were forced to move to a new location.<ref>{{Cite news |date=7 June 2012 |title=A Rare Genetic Disorder Is Stalking the Children of the Navajo Nation In POV's 'Sun Kissed,' Premiering Thursday, Oct. 18, 2012, on PBS |url=http://www.pbs.org/pov/blog/pressroom/2012/06/sun-kissed-premieres-on-pov/ |url-status=dead |archive-url=https://web.archive.org/web/20180629211242/http://www.pbs.org/pov/blog/pressroom/2012/06/sun-kissed-premieres-on-pov/ |archive-date=2018-06-29 |access-date=2018-06-29 |language=en-US}}</ref><ref>{{Cite news |last=Ziff |first=Deborah |name-list-style=vanc |title=Hiding From the Sun |url=https://www.abqjournal.com/159912/hiding-from-the-sun.html |access-date=2018-06-29 |work=The Albuquerque Journal |language=en-US}}</ref><ref>{{Cite news |last=Bender |first=Albert |name-list-style=vanc |date=2013-03-06 |title=Rare disease suddenly arises on Navajo Reservation |url=https://www.peoplesworld.org/article/rare-disease-suddenly-arises-on-navajo-reservation/ |access-date=2018-06-29 |work=People's World |language=en-US}}</ref> The 2016 Vietnamese romance drama ''[[:vi:Khúc hát mặt trời|Khúc hát mặt trời]]'', based on a 2006 Japanese film, ''[[A Song to the Sun]]'', tells the story of a girl named Yến Phương with XP and the impact of her sickness on her life and relationships, following the story of Phương's accidental exposure to sunlight and subsequent neurological degeneration.<ref>{{Citation |title=Khúc hát mặt trời |date=7 November 2015 |url=https://www.vov.vn/van-hoa/dien-anh/khuc-hat-mat-troi-chuyen-tinh-cam-dong-cua-nha-phuong-quang-tuan-448057.vov |access-date=2021-08-09 |language=vi}}</ref> ''[[Midnight Sun (2018 film)]]'' is a 2018 American romantic drama film based on the 2006 Japanese film A Song to the Sun. The film was directed by Scott Speer and written by Eric Kirsten, and stars Bella Thorne, Patrick Schwarzenegger, and Rob Riggle.{{cn|date=October 2024}}
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