Editing Adaptive enzyme

An '''adaptive enzyme''' or '''inducible enzyme''' is an [[enzyme]] that is [[gene expression|expressed]] only under conditions in which it is clearly of adaptive value, as opposed to a [[constitutive enzyme]] which is produced all the time.<ref>{{Cite journal |last1=Gibson |first1=David M. |last2=Hicks |first2=Sonja E. |last3=Allmann |first3=David W. |date=1966-01-01 |title=Adaptive enzyme formation during hyperlipogenesis |url=https://dx.doi.org/10.1016/0065-2571%2866%2990019-7 |journal=Advances in Enzyme Regulation |language=en |volume=4 |pages=239–246 |doi=10.1016/0065-2571(66)90019-7 |issn=0065-2571|url-access=subscription }}</ref><ref>{{Cite journal |last1=Liou |first1=G. I. |last2=Donaldson |first2=W. E. |date=1977-01-15 |title=Avian fatty acid synthetase: Evidence for short-term regulation of activity |url=https://dx.doi.org/10.1016/0003-9861%2877%2990184-9 |journal=Archives of Biochemistry and Biophysics |language=en |volume=178 |issue=1 |pages=195–199 |doi=10.1016/0003-9861(77)90184-9 |pmid=836033 |issn=0003-9861|url-access=subscription }}</ref>

The inducible enzyme is used for the breaking-down of things in the cell. It is also a part of the Operon Model, which illustrates a way for genes to turn "on" and "off".
The inducer causes the gene to turn on (controlled by the amount of reactant which turns the gene on). Then there's the repressor protein that turns genes off. The inducer can remove this repressor, turning genes back on. The operator is a section of DNA where the repressor binds to shut off certain genes; the promoter is the section of DNA where the [[RNA polymerase]] binds. Lastly, the regulatory gene is the gene for the repressor protein.
An example of inducible enzyme is [[COX-2]] which is synthesized in [[macrophages]] to produce [[Prostaglandin E2|prostaglandin E<sub>2</sub>]] while the [[constitutive enzyme]] [[COX-1]] (another isozyme in [[COX]] family) is always produced in variety of organs in body (like stomach).
{{Wiktionarypar|adaptive enzyme}}

== References ==
{{Reflist}}

{{DEFAULTSORT:Adaptive Enzyme}}
[[Category:Enzymes]]


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