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Hypertrophy
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{{short description|Increase in the volume of an organ or tissue due to the enlargement of its component cells}} {{more medical citations needed|date=May 2017}} {{Infobox medical condition (new) | name = Hypertrophy | image = Hyperplasia vs Hypertrophy.svg | caption = Hypertrophy results from an increase in cell size, whereas [[hyperplasia]] stems from an increase in cell number.| | pronounce = | field = | synonyms = | symptoms = | complications = | onset = | duration = | types = | causes = | risks = | diagnosis = | differential = | prevention = | treatment = | medication = | prognosis = | frequency = | deaths = }} '''Hypertrophy''' is the increase in the volume of an organ or tissue due to the enlargement of its component [[Cell (biology)|cells]].<ref name="Muscle Hypertrophy">{{cite web|last1=Hernandez|first1=Richard|last2=Kravitz|first2=Len|title=Skeletal muscle hypertrophy|url=https://www.unm.edu/~lkravitz/Article%20folder/hypertrophy.html|website=www.unm.edu}}</ref> It is distinguished from [[hyperplasia]], in which the cells remain approximately the same size but increase in number.<ref>{{Cite web|title=Hyperplasia: MedlinePlus Medical Encyclopedia|url=https://medlineplus.gov/ency/article/003441.htm|access-date=2023-02-19|website=medlineplus.gov|language=en}}</ref> Although hypertrophy and hyperplasia are two distinct processes, they frequently occur together, such as in the case of the [[hormone|hormonally]] induced proliferation and enlargement of the cells of the [[uterus]] during [[pregnancy]]. '''Eccentric hypertrophy''' is a type of hypertrophy where the walls and chamber of a hollow organ undergo growth in which the overall size and volume are enlarged. It is applied especially to the [[left ventricle]] of heart.<ref name=Kusumoto2004 >{{citation | last=Kusumoto | first=F. M. | year=2004 | title=Cardiovascular Pathophysiology | publisher=Hayes Barton Press | isbn=978-1-59377-189-8 | url=https://books.google.com/books?id=FHT_w_gUeK4C&q=Eccentric+hypertrophy&pg=PA22 | pages=20β22 }}{{Dead link|date=August 2024 |bot=InternetArchiveBot |fix-attempted=yes }}</ref> [[Sarcomere]]s are added in series, as for example in [[dilated cardiomyopathy]] (in contrast to [[hypertrophic cardiomyopathy]], a type of [[concentric hypertrophy]], where sarcomeres are added in parallel). ==Gallery== <gallery> Gould Pyle 234.jpg|[[Breast hypertrophy|Breasts]] Hypertrophied clitoris.jpg|[[Clitoromegaly|Clitoris]] Head of a boy with hypertrophy of the ear Wellcome L0062496.jpg|[[Ear]] Gould Pyle 127.jpg|[[Fingers]] Feet from a case of partial hypertrophy of the foot Wellcome L0061374.jpg|[[Foot]] (partial) Hypertrophy of the gums Wellcome L0062728.jpg|[[Gingival enlargement|Gums]] Hypertrophy from Carswell, 1838. Wellcome L0000931.jpg|[[Hypertrophic cardiomyopathy|Heart]] Kidney hypertrophy Wellcome L0005308.jpg|[[Kidneys]] Face of man with hypertrophy of the temporal muscles Wellcome L0062508.jpg|[[Temporal muscles]] Tibia affected by chronic inflammatory hypertrophy Wellcome L0061256.jpg|[[Tibia]] (inflammatory) Inflammatory hypertrophy of the tongue Wellcome L0061277.jpg|[[Macroglossia|Tongue]] (inflammatory) Gould Pyle 100.jpg|[[Upper lip]] Operative gynecology - (1906) (14780430391).jpg|[[Urethral meatus]] </gallery> {{-plasia}} ==See also== * [[Athlete's heart]] * [[Ventricular hypertrophy]] (including [[left ventricular hypertrophy]] and [[right ventricular hypertrophy]]) * [[Muscle hypertrophy]] * [[List of biological development disorders]] ==References== {{reflist}} == External links == {{Medical resources | DiseasesDB = | ICD10 = | ICD9 = | ICDO = | OMIM = | MedlinePlus = | eMedicineSubj = | eMedicineTopic = | MeshID = D006984 | SNOMED CT = 56246009 }} *[http://muscle.ucsd.edu/musintro/hypertrophy.shtml University of California Muscle Physiology Home Page: Hypertrophy] {{Webarchive|url=https://web.archive.org/web/20210421192506/http://muscle.ucsd.edu/Musintro/hypertrophy.shtml |date=2021-04-21 }} {{Pathology}} {{Authority control}} [[Category:Muscular system]] [[Category:Tissues (biology)]] [[Category:Exercise physiology]] [[Category:Physical exercise]] [[Category:Anatomical pathology]]
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