Editing Susan Lindquist

{{Use mdy dates|date=June 2021}}
{{short description|American geneticist}}
{{Infobox scientist
|name              = Susan Lindquist
|image             = Professor Susan Lindquist ForMemRS.jpg
|caption           = Susan Lindquist in 2015, portrait via the [[Royal Society]]
|birth_date        = {{Birth date|1949|06|05}}
|birth_place       = [[Chicago|Chicago, Illinois]], U.S.
|birth_name        = Susan Lee Lindquist
|death_date        = {{death date and age|2016|10|27|1949|06|05}}
|death_place       = [[Boston|Boston, Massachusetts]], U.S.
|field             = [[Molecular biology]]
|work_institutions = {{Plainlist|
* [[Whitehead Institute]]
* [[Massachusetts Institute of Technology|MIT]]
* [[HHMI]]
* [[University of Chicago]]}}
|education         = {{Plainlist|
* [[Harvard University]]
* [[University of Illinois at Urbana–Champaign]]}}
| thesis_title = Protein and RNA synthesis induced by heat treatment in Drosophila melanogaster tissue culture cells
| thesis_year = 1976
| thesis_url = https://www.worldcat.org/oclc/14767508
| doctoral_advisor = [[Matthew Meselson]]<ref name="interview">{{Cite journal|last1=Gitschier |first1=J.|title=A Flurry of Folding Problems: An Interview with Susan Lindquist
|doi=10.1371/journal.pgen.1002076|journal=PLOS Genetics|volume=7|issue=5|pages=e1002076|year=2011|pmid=21589898|pmc=3093363 |doi-access=free }}</ref>
| doctoral_students =
| known_for         = [[protein folding]]<br />[[heat-shock protein]]s<br />[[prion]]s
| prizes            = {{Plainlist|
* [[Dickson Prize]] <small>(2003)</small>
* [[Genetics Society of America Medal]] <small>(2008)</small><ref name="genetics">{{Cite journal |last1=Hopkins |first1=N. |title=The 2008 Genetics Society of America Medal |doi=10.1534/genetics.104.017834 |journal=Genetics |volume=178 |issue=3 |pages=1125–1128 |year=2008 |pmid=18385104|pmc=2278094}}</ref>
* [[FASEB Excellence in Science Award]] <small>(2009)</small>
* [[National Medal of Science]] <small>(2010)</small>
* [[Mendel Medal (genetics)|Mendel Medal]] {{small|(2010)}}
* [[E. B. Wilson Medal]] <small>(2012)</small>}}
| website = {{URL|http://lindquistlab.wi.mit.edu}}
}}

'''Susan Lee Lindquist''', [[List of Fellows of the Royal Society elected in 2015|ForMemRS]] (June 5, 1949 – October 27, 2016) was an American professor of biology at [[MIT]]<ref>{{cite web|url=http://www.whitehead.mit.edu/research/faculty/lindquist.html|title=Whitehead Institute – Faculty |website=Whitehead.mit.edu|access-date=October 30, 2016}}</ref><ref>{{cite web|url=http://web.wi.mit.edu/lindquist/pub/|title=Lindquist Lab &#124; Lindquist Lab at the Whitehead Institute for Biomedical Research &#124; Lindquist Lab|website=mit.edu|date=February 10, 2016|access-date=October 30, 2016|archive-date=July 16, 2012|archive-url=https://web.archive.org/web/20120716221555/http://web.wi.mit.edu/lindquist/pub/|url-status=dead}}</ref> specializing in [[molecular biology]], particularly the  [[protein folding]] problem<ref name="interview"/><ref>{{Cite journal|last1=Kain|first1=K. |title=Using yeast to understand protein folding diseases: An interview with Susan Lindquist|doi=10.1242/dmm.000810|journal=Disease Models and Mechanisms|volume=1|issue=1|pages=17–19|year=2008|pmid=19048046|pmc=2561974}}</ref> within a family of molecules known as [[heat-shock protein]]s,<ref>{{Cite journal|last1=Lindquist|first1=S. |doi=10.1146/annurev.bi.55.070186.005443|title=The Heat-Shock Response|journal=Annual Review of Biochemistry|volume=55|pages=1151–91|year=1986|pmid=2427013|s2cid=42450279 }}</ref><ref>{{Cite journal|last1=Parsell|first1=D.A.|last2=Lindquist|first2=S.|doi=10.1146/annurev.ge.27.120193.002253|title=The Function of Heat-Shock Proteins in Stress Tolerance: Degradation and Reactivation of Damaged Proteins|journal=Annual Review of Genetics|volume=27|pages=437–96|year=1993|pmid=8122909|s2cid=31351089}}</ref> and [[prion]]s.<ref name=obituary>{{cite journal|last1=Whitesell|first1=Luke|last2=Santagata|first2=Sandro|pmid= 27884995 |title=Susan Lindquist (1949–2016)|journal=Science|volume=354|issue=6315|year=2016 |pages=974|issn=0036-8075|doi=10.1126/science.aal3609|bibcode=2016Sci...354..974W|s2cid=5375718}}</ref> Lindquist was a member and former director of the [[Whitehead Institute]] and was awarded the [[National Medal of Science]] in 2010.<ref>{{cite web|url=http://www.ibiology.org/ibioseminars/cell-biology/susan-lindquist-part-1.html|title=Prions and Protein Folding: Video talk by Dr. Susan Lindquist|website=Ibiology.org|date=June 16, 2015|access-date=October 30, 2016|url-status=dead |archive-url=https://web.archive.org/web/20161029113202/https://www.ibiology.org/ibioseminars/cell-biology/susan-lindquist-part-1.html|archive-date=October 29, 2016}}</ref><ref>{{cite web|url=http://www.wi.mit.edu/research/faculty/lindquist.html|title=Whitehead Institute – Faculty|website=mit.edu|access-date=October 30, 2016}}</ref><ref>{{cite web|url=https://www.youtube.com/watch?v=yJP3efIaDm0 |archive-url=https://ghostarchive.org/varchive/youtube/20211211/yJP3efIaDm0| archive-date=2021-12-11 |url-status=live|title=Susan Lindquist – 2009 National Medal of Science|publisher=[[YouTube]]|date=November 29, 2010|access-date=October 30, 2016}}{{cbignore}}</ref>

==Early life and education==
Lindquist was born in Chicago, Illinois, to Iver and Eleanor (née Maggio), and attended [[Maine South High School]] in [[Park Ridge, Illinois|Park Ridge]].<ref name=":0">{{Cite news|url=https://www.nytimes.com/2016/10/30/science/susan-lindquist-scientist-who-made-genetic-discoveries-using-yeast-dies-at-67.html|title=Susan Lindquist, Scientist Who Made Genetic Discoveries Using Yeast, Dies at 67|last=Grimes|first=William|date=October 28, 2016|newspaper=The New York Times|issn=0362-4331|access-date=October 30, 2016}}</ref>

Lindquist's father and mother were of Swedish and Italian descent, respectively,<ref>{{cite web|url=http://www.ascb.org/memoriam-susan-lindquist-67-pioneer-protein-folding-research/|title=In Memoriam: Susan Lindquist, 67, Pioneer in Protein Folding Research – ASCB|first=John|last=Fleischman|work=ASCB Post|date=October 28, 2016|url-status=dead |archive-url=https://web.archive.org/web/20161103220009/http://www.ascb.org/memoriam-susan-lindquist-67-pioneer-protein-folding-research/|archive-date=November 3, 2016}}</ref> and although they expected her to become a housewife,<ref>{{cite journal|last=Gitschier|first=Jane|title=A Flurry of Folding Problems: An Interview with Susan Lindquist|journal=PLOS Genetics|volume=7|issue=5|pages=e1002076|doi=10.1371/journal.pgen.1002076|pmid=21589898|pmc=3093363|year=2011 |doi-access=free }}</ref> Susan studied microbiology at the [[University of Illinois at Urbana–Champaign|University of Illinois]] as an undergraduate and received her PhD in biology from [[Harvard University]] in 1976.<ref name=phd>{{cite thesis|degree=PhD |first=Susan Lee Lindquist|last=McKenzie|title=Protein and RNA synthesis induced by heat treatment in Drosophila melanogaster tissue culture cells|publisher=Harvard University|date=1976|oclc=14767508}}</ref> She completed a post-doctoral fellowship at the [[American Cancer Society]].<ref name=":5"/>

== Career ==
Upon completing her dissertation in 1976, Lindquist moved to the [[University of Chicago]] for a short post-doc before being hired as a faculty member in the Biology Department in 1978,<ref name=":1">{{Cite journal|last=Fuchs|first=Elaine|date=December 2016|title=Susan Lee Lindquist (1949–2016)|journal=Cell|language=en|volume=167|issue=6|pages=1440–1442|doi=10.1016/j.cell.2016.11.030|pmid=29413691|bibcode=2016Natur.540...40S|issn=0092-8674|doi-access=free}}</ref> becoming the Albert D. Lasker Professor of Medical Sciences with the founding of the Department of Molecular Genetics and Cell Biology in 1980.<ref name=":5" /> At the University of Chicago Lindquist investigated the role of [[heat shock protein]]s in regulating the cellular response to environmental stresses. Lindquist pioneered the use of [[Saccharomyces cerevisiae|yeast]] as a model system to study how heat shock proteins regulate gene expression and protein folding. For this work, Lindquist was made an investigator for the [[Howard Hughes Medical Institute]] in 1988.<ref name=":1" /> After making important new discoveries to [[Prion proteins|prions]], Lindquist moved to [[Massachusetts Institute of Technology|MIT]] in 2001 and was appointed as Director of the [[Whitehead Institute for Biomedical Research]], one of the first women in the nation to lead a major independent research organization.<ref>{{cite web|url=http://www.hhmi.org/research/investigators/lindquist_bio.html|title=Susan Lindquist, PhD|website=HHMI.org|access-date=October 30, 2016}}</ref>

In 2004, Lindquist resumed research as an Institute Member, an associate member of the [[Broad Institute]] of MIT and [[Harvard]], and an associate member of the [[David H. Koch Institute for Integrative Cancer Research]] at MIT.<ref name=":4" />

Lindquist was awarded the National Medal of Science in 2009 (presented in 2010), for research contributions to protein folding.<ref>{{Cite web|url=https://www.nsf.gov/od/nms/recip_details.jsp?recip_id=5300000000465|title=The President's National Medal of Science: Recipient Details {{!}} NSF – National Science Foundation|website=www.nsf.gov|access-date=August 7, 2018}}</ref>

Lindquist lectured nationally and internationally on a variety of scientific topics.  In June 2006, she was the inaugural guest on the "Futures in Biotech" podcast on [[Leo Laporte]]'s [[TWiT]] network.<ref>{{Cite web|url=https://twit.tv/shows/futures-in-biotech/episodes/1|title=Futures in Biotech 1 Dr. Susan Lindquist {{!}} TWiT.TV|website=TWiT.tv|access-date=October 31, 2016}}</ref> In 2007, she participated in the [[World Economic Forum]] in Davos, Switzerland with other MIT leaders.<ref>{{cite web|url=http://web.mit.edu/fnl/volume/196/sheffi.html|title=MIT and the World Economic Forum|author=Yossi Sheffi|website=mit.edu|access-date=October 30, 2016}}</ref>

Lindquist also co-founded two companies to translate research into potential therapies, FoldRx and Yumanity Therapeutics (with [[N. Anthony Coles]]),<ref name=carroll>Carroll, John. UPDATED: Onyx vet Tony Coles embarks on a new biotech adventure. Fierce BioTech. December 15, 2014. https://www.fiercebiotech.com/biotech/updated-onyx-vet-tony-coles-embarks-on-a-new-biotech-adventure</ref> companies developing drug therapies for diseases of protein misfolding and amyloidosis.<ref name="Scientific Founders – FoldRx">{{Cite web|url=http://www.foldrx.com/about-scientific.htm|title=Scientific Founders – FoldRx|archive-url=https://web.archive.org/web/20110711014625/http://www.foldrx.com/about-scientific.htm|archive-date=July 11, 2011|url-status=dead|access-date=October 31, 2016}}</ref><ref name="Yumanity Therapeutics">{{Cite web|url=http://www.yumanity.com/|title=Yumanity Therapeutics|website=www.yumanity.com|access-date=July 2, 2017}}</ref>

In November 2016, [[Johnson & Johnson]] gave a $5 million gift to Whitehead Institute to establish the Susan Lindquist Chair for Women in Science in Lindquist's memory. The gift will be awarded to a female scientist at Whitehead Institute.<ref>{{cite news|url=https://www.bostonglobe.com/business/2016/11/16/hill-holliday-advertising-industry-face-bold-reinvention/LAQEMt3NJ2b3omlfIEKqcM/story.html|title=A chair at MIT in Lindquist's memory|last1=WEISMAN|first1=ROBERT|date=November 17, 2016|work=Boston Globe|access-date=September 21, 2017}}</ref>

==Research==
Lindquist is best known for her research that provided strong evidence for a new paradigm in [[genetics]] based upon the [[Biological inheritance|inheritance]] of [[protein]]s with new, self-perpetuating shapes rather than new [[DNA sequence]]s. This research provided a [[biochemistry|biochemical]] framework for understanding devastating neurological illnesses such as [[Alzheimer's disease|Alzheimer's]], [[Parkinson's disease|Parkinson's]], [[Huntington's disease|Huntington's]], and [[Creutzfeldt–Jakob disease]]s.<ref name=":0"/> She was considered an expert in protein folding, which, as explained by Lindquist in the following excerpt, is an ancient, fundamental problem in biology:

<blockquote>What do "mad cows", people with [[neurodegenerative disease]]s, and an unusual type of inheritance in [[yeast]] have in common? They are all experiencing the consequences of misfolded proteins. ... In humans the consequences can be deadly, leading to such devastating illnesses as Alzheimer's Disease. In one case, the misfolded protein is not only deadly to the unfortunate individual in which it has appeared, but it can apparently be passed from one individual to another under special circumstances – producing infectious neurodegenerative diseases such as [[Bovine spongiform encephalopathy|mad-cow disease]] in [[cattle]] and Creutzfeldt–Jacob Disease in humans.<ref>[https://web.archive.org/web/20010702050331/http://www4.nas.edu/opus/home.nsf/web/slindquist?OpenDocument "From Mad Cows to 'Psi-chotic' Yeast: A New Paradigm in Genetics"], ''NAS Distinguished Leaders in Science Lecture Series'', November 10, 1999.</ref></blockquote>

Lindquist worked on the PSI+ element in yeast (a [[prion]]) and how it can act as a switch that hides or reveals numerous [[mutation]]s throughout the [[genome]], thus acting as an [[evolutionary capacitor]]. She proposed that a [[heat shock protein]], [[hsp90]], may act in the same way, normally preventing [[phenotype|phenotypic]] consequences of genetic changes, but showing all changes at once when the HSP system is overloaded, either pharmacologically or under stressful environmental conditions.<ref>{{cite web|url=https://biology.mit.edu/people/susan_lindquist#research_summary|title=Susan Lindquist profile|website=[[MIT Biology]]|access-date=October 30, 2016|url-status=dead|archive-url=https://web.archive.org/web/20161030143516/https://biology.mit.edu/people/susan_lindquist#research_summary|archive-date=October 30, 2016}}</ref>
[[File:Plos lindquist.jpg|thumb|Susan Lindquist]]

Most of these variations are likely to be harmful, but a few unusual combinations may produce valuable new traits, spurring the pace of evolution. Cancer cells too have an extraordinary ability to evolve. Lindquist's lab investigates closely related evolutionary mechanisms involved in the progression of cancerous tumors<ref>{{Cite web|url=http://wi.mit.edu/news/archive/2014/master-heat-shock-factor-supports-reprogramming-normal-cells-enable-tumor-growth|title=Whitehead Institute – News – 2014 – Master heat-shock factor supports reprogramming of normal cells to enable tumor growth and metastasis|website=wi.mit.edu|date=July 31, 2014 |access-date=October 31, 2016}}</ref> and in the evolution of antibiotic-resistant fungi.<ref>{{Cite journal|last=Heitman|first=Joseph|date=September 30, 2005|title=A Fungal Achilles' Heel|journal=Science|volume=309|issue=5744|pages=2175–2176|doi=10.1126/science.1119321|issn=0036-8075|pmid=16195450|s2cid=27186932}}</ref>

Lindquist made advances in [[nanotechnology]], researching organic amyloid fibers capable of self-organizing into structures smaller than manufactured materials. Her group also developed a yeast "living test tube" model to study protein folding transitions in neurodegenerative diseases and to test therapeutic strategies through high-throughput screening.<ref name=":3"/>

===Publications===
{{div col|colwidth=35em}}
* {{cite journal
|vauthors=Tardiff DF, Jui NT, Khurana V, Tambe MA, Thompson ML, Chung CY, Kamadurai HB, Kim HT, Lancaster AK, Caldwell KA, Caldwell GA, Rochet JC, Buchwald SL, Lindquist S
|title=Yeast reveal a "druggable" Rsp5/Nedd4 network that ameliorates α-synuclein toxicity in neurons
|journal=Science
|volume=342
|issue=6161
|pages=979–83
|year=2013
|pmid=24158909
|pmc=3993916
|doi=10.1126/science.1245321
|bibcode=2013Sci...342..979T
}}
* {{cite journal
|vauthors=Chung CY, Khurana V, Auluck PK, Tardiff DF, Mazzulli JR, Soldner F, Baru V, Lou Y, Freyzon Y, Cho S, Mungenast AE, Muffat J, Mitalipova M, Pluth MD, Jui NT, Schüle B, Lippard SJ, Tsai LH, Krainc D, Buchwald SL, Jaenisch R, Lindquist S
|title=Identification and rescue of α-synuclein toxicity in Parkinson patient-derived neurons
|journal=Science
|volume=342
|issue=6161
|pages=983–7
|year=2013
|pmid=24158904
|pmc=4022187
|doi=10.1126/science.1245296
|bibcode=2013Sci...342..983C
}}
* {{Cite journal | last1 = Jarosz | first1 = D. F. | last2 = Lindquist | first2 = S. | doi = 10.1126/science.1195487 | title = Hsp90 and Environmental Stress Transform the Adaptive Value of Natural Genetic Variation | journal = Science | volume = 330 | issue = 6012 | pages = 1820–1824 | year = 2010 | pmid =  21205668| pmc = 3260023| bibcode = 2010Sci...330.1820J | url = http://dspace.mit.edu/bitstream/1721.1/84954/1/Lindquist_Hsp90%20and%20environmental.pdf }}
* {{Cite journal
| last1 = Alberti | first1 = S.
| last2 = Halfmann | first2 = R.
| last3 = King | first3 = O.
| last4 = Kapila | first4 = A.
| last5 = Lindquist | first5 = S.
| title = A Systematic Survey Identifies Prions and Illuminates Sequence Features of Prionogenic Proteins
| doi = 10.1016/j.cell.2009.02.044
| journal = Cell
| volume = 137
| issue = 1
| pages = 146–158
| year = 2009
| pmid = 19345193
| pmc =2683788
}}.
* {{Cite journal
| last1 = Gitler | first1 = A. D.
| last2 = Chesi | first2 = A.
| last3 = Geddie | first3 = M. L.
| last4 = Strathearn | first4 = K. E.
| last5 = Hamamichi | first5 = S.
| last6 = Hill | first6 = K. J.
| last7 = Caldwell | first7 = K. A.
| last8 = Caldwell | first8 = G. A.
| last9 = Cooper | first9 = A. A.
| last10 = Rochet
| doi = 10.1038/ng.300 | first10 = J. C.
| last11 = Lindquist | first11 = S.
| title = Α-Synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity
| journal = Nature Genetics
| volume = 41
| issue = 3
| pages = 308–315
| year = 2009
| pmid = 19182805
| pmc =2683786
}}
* {{Cite journal
| last1 = Dai | first1 = C.
| last2 = Whitesell | first2 = L.
| last3 = Rogers | first3 = A. B.
| last4 = Lindquist | first4 = S.
| title = Heat Shock Factor 1 is a Powerful Multifaceted Modifier of Carcinogenesis
| doi = 10.1016/j.cell.2007.07.020
| journal = Cell
| volume = 130
| issue = 6
| pages = 1005–1018
| year = 2007
| pmid = 17889646
| pmc =2586609
}}
* {{Cite journal
| last1 = Cooper | first1 = A. A.
| last2 = Gitler | first2 = A.
| last3 = Cashikar | first3 = A.
| last4 = Haynes | first4 = C.
| last5 = Hill | first5 = K.
| last6 = Bhullar | first6 = B.
| last7 = Liu | first7 = K.
| last8 = Xu | first8 = K.
| last9 = Strathearn | first9 = K.
| last10 = Liu | first10 = F.
| last11 = Cao | first11 = S.
| last12 = Caldwell | first12 = K. A.
| last13 = Caldwell | first13 = G. A.
| last14 = Marsischky | first14 = G.
| last15 = Kolodner | first15 = R. D.
| last16 = Labaer | first16 = J.
| last17 = Rochet | first17 = J. C.
| last18 = Bonini | first18 = N. M.
| last19 = Lindquist | first19 = S.
| title =  -Synuclein Blocks ER-Golgi Traffic and Rab1 Rescues Neuron Loss in Parkinson's Models
| doi = 10.1126/science.1129462
| journal = Science
| volume = 313
| issue = 5785
| pages = 324–328
| year = 2006
| pmid = 16794039
| pmc =1983366 | bibcode = 2006Sci...313..324C
}}
* {{Cite journal
| last1 = Cowen | first1 = L. E.
| last2 = Lindquist | first2 = S.
| title = Hsp90 Potentiates the Rapid Evolution of New Traits: Drug Resistance in Diverse Fungi
| doi = 10.1126/science.1118370
| journal = Science
| volume = 309
| issue = 5744
| pages = 2185–2189
| year = 2005
| pmid = 16195452
| bibcode = 2005Sci...309.2185C
| s2cid = 52847795
}}
* {{Cite journal
| last1 = Krishnan | first1 = R.
| last2 = Lindquist | first2 = S. L.
| doi = 10.1038/nature03679
| title = Structural insights into a yeast prion illuminate nucleation and strain diversity
| journal = Nature
| volume = 435
| issue = 7043
| pages = 765–772
| year = 2005
| pmid = 15944694
| pmc =1405905
| bibcode = 2005Natur.435..765K
}}
* {{Cite journal
| doi = 10.1016/S0092-8674(03)01020-1
| last1 = Si | first1 = K.
| last2 = Lindquist | first2 = S.
| last3 = Kandel | first3 = E.
| title = A neuronal isoform of the aplysia CPEB has prion-like properties
| journal = Cell
| volume = 115
| issue = 7
| pages = 879–891
| year = 2003
| pmid = 14697205
| s2cid = 3060439 | doi-access = free
}}
* {{Cite journal
| last1 = Queitsch | first1 = C.
| last2 = Sangster | first2 = T. A.
| last3 = Lindquist | first3 = S.
| doi = 10.1038/nature749
| title = Hsp90 as a capacitor of phenotypic variation
| journal = Nature
| volume = 417
| issue = 6889
| pages = 618–624
| year = 2002
| pmid = 12050657
| bibcode = 2002Natur.417..618Q
| s2cid = 4419085
}}
* {{Cite journal
| last1 = Serio | first1 = T.
| last2 = Cashikar | first2 = A.
| last3 = Kowal | first3 = A.
| last4 = Sawicki | first4 = G.
| last5 = Moslehi | first5 = J.
| last6 = Serpell | first6 = L.
| last7 = Arnsdorf | first7 = M.
| last8 = Lindquist | first8 = S.
| title = Nucleated conformational conversion and the replication of conformational information by a prion determinant
| journal = Science
| volume = 289
| issue = 5483
| pages = 1317–1321
| year = 2000
| pmid = 10958771 | doi=10.1126/science.289.5483.1317
| bibcode = 2000Sci...289.1317S
}}
* {{Cite journal | last1 = Patino | first1 = M. M. | last2 = Liu | first2 = J. -J. | last3 = Glover | first3 = J. R. | last4 = Lindquist | first4 = S. | title = Support for the Prion Hypothesis for Inheritance of a Phenotypic Trait in Yeast | doi = 10.1126/science.273.5275.622 | journal = Science | volume = 273 | issue = 5275 | pages = 622–626 | year = 1996 | pmid =  8662547| bibcode = 1996Sci...273..622P | s2cid = 9760894 | pmc = 1050929 }}
* {{Cite journal
| last1 = Lindquist | first1 = S.
| title = Regulation of protein synthesis during heat shock
| journal = Nature
| volume = 293
| issue = 5830
| pages = 311–314
| year = 1981
| pmid = 6792546
 | doi=10.1038/293311a0
| bibcode = 1981Natur.293..311L
| s2cid = 4263197
}}
{{div col end}}

==Awards and honors==
Lindquist won numerous awards and honors including:
{{div col|colwidth=35em}}
* Elected to the [[American Academy of Arts and Sciences]] in 1996.<ref name=":0"/>
* Elected to the [[United States National Academy of Sciences|National Academy of Sciences]] in 1997.<ref name=":0"/>
* Named a fellow of the [[American Academy of Microbiology]] in 1997.<ref>{{Cite web|url=http://accounts.asm.org/directory/academy/|title=Navigation for iFrame|website=accounts.asm.org|access-date=October 31, 2016}}</ref>
* Received the [[Novartis]]/Drew Award in Biomedical Research in 2000.<ref name=":1"/>
* Received the [[Dickson Prize in Medicine]] in 2003.<ref name="dicksonprize">{{cite web|url=http://www.dicksonprize.pitt.edu/recipients/2003-lindquist.php|title=Susan L. Lindquist, PhD {{!}} Dickson Prize in Medicine|last=Webteam|first=University of Pittsburgh University Marketing Communications |website=www.dicksonprize.pitt.edu|access-date=October 30, 2016}}</ref>
* Elected to the [[American Philosophical Society]] in 2003.<ref name="Obituary">{{cite news |title=Susan Lindquist, pioneering biologist and former director of Whitehead Institute, dies at 67 Biology professor and mentor to many investigated protein folding and its role in disease |url=https://news.mit.edu/2016/susan-lindquist-whitehead-institute-obituary-1028 |access-date=May 1, 2019 |work=MIT News |date=October 28, 2016}}</ref>
* Named one of the 50 most important women in science by ''Discover'' Magazine in 2002.<ref name="Svitil">{{cite news|last1=Svitil|first1=Kathy|title=The 50 Most Important Women in Science|url=http://discovermagazine.com/2002/nov/feat50/|access-date=May 1, 2019|publisher=Discover|date=November 13, 2002}}</ref>
* Awarded the [[Sigma Xi]] [[William Procter Prize for Scientific Achievement]] in 2006.<ref name=":2">{{Cite web|url=https://www.jnj.com/leadership/susan-l-lindquist|title=Susan L. Lindquist profile|website=jnj.com|access-date=October 31, 2016}}</ref>
* Elected to the [[Institute of Medicine]] of the National Academies in 2006.<ref name=":2"/>
* Awarded the [[Genetics Society of America]] Medal in 2008.<ref name="genetics"/>
* Awarded the [[Otto Warburg Medal]] by the German Society for Biochemistry and Molecular Biology in 2008.<ref>{{Cite web|url=https://www.abnnewswire.net/press/en/49615/US-Scientist-Receives-Otto-Warburg-Medal-Sponsored-By-QIAGEN.html/|title=U.S. Scientist Receives Otto Warburg Medal Sponsored By QIAGEN|website=www.abnnewswire.net|access-date=October 31, 2016}}</ref>
* Awarded the [[FASEB Excellence in Science Award]] in 2009.<ref name=":5">{{Cite web|url=https://faseb.org/portals/2/PDFs/FASEB%20Press%20Release%20-%20Susan%20L.%20Lindquist%20PhD.pdf|title=FASEB ANNOUNCES RECIPIENT OF THE 2009 EXCELLENCE IN SCIENCE AWARD|date=July 18, 2008|publisher=Federation of American Societies for Experimental Biology|access-date=October 31, 2016|archive-date=June 30, 2014|archive-url=https://web.archive.org/web/20140630095136/http://faseb.org/portals/2/PDFs/FASEB%20Press%20Release%20-%20Susan%20L.%20Lindquist%20PhD.pdf|url-status=dead}}</ref>
* Awarded the [[Max Delbrück Medal]], Berlin, Germany, in 2010.<ref>{{cite web|url=http://www.mdc-berlin.de/en/news/2010/20101103-professor_susan_lindquist_from_the_whitehe/index.html|title=Professor Susan Lindquist from the Whitehead Institute Receives Max Delbrück Medal in Berlin|website=Mdc-berlin.de|access-date=October 30, 2016|url-status=dead|archive-url=https://web.archive.org/web/20110103122008/http://www.mdc-berlin.de/en/news/2010/20101103-professor_susan_lindquist_from_the_whitehe/index.html|archive-date=January 3, 2011}}</ref>
* Awarded the Mendel Medal by [[The Genetics Society]], UK, in 2010.<ref>{{Cite web|url=http://www.genetics.org.uk/page/2774/2010-Mendel-Lecture.html|title=2010 Mendel Lecture – The Genetics Society|archive-url=https://web.archive.org/web/20110813073758/http://www.genetics.org.uk/page/2774/2010-Mendel-Lecture.html|archive-date=August 13, 2011|url-status=dead|access-date=October 31, 2016}}</ref>
* Awarded the [[National Medal of Science]] (for 2009) in 2010.<ref>{{cite news|url=http://www.boston.com/news/nation/washington/articles/2010/11/18/cambridge_researcher_honored_at_white_house|work=The Boston Globe|first=Miriam|last=Valverde|title=Cambridge researcher honored at White House|date=November 18, 2010}}</ref>
* Made an Associate Member of the [[European Molecular Biology Organization]] in 2011.<ref>{{cite web|url=https://biology.mit.edu/about/awards/2840|title=Recipients of European Molecular Biology Organization Associate Member award|website=biology.mit.edu|access-date=October 30, 2016|url-status=dead|archive-url=https://web.archive.org/web/20161030143753/https://biology.mit.edu/about/awards/2840|archive-date=October 30, 2016}}</ref>
* Awarded the [[E.B. Wilson Medal]] by [[The American Society for Cell Biology]] in 2012.<ref>{{cite web|url=https://biology.mit.edu/about/awards/2843|title=Recipients of American Society for Cell Biology E.B. Wilson Medal award {{!}} MIT Biology|website=biology.mit.edu|access-date=October 30, 2016|url-status=dead|archive-url=https://web.archive.org/web/20161030142036/https://biology.mit.edu/about/awards/2843|archive-date=October 30, 2016}}</ref>
* Awarded the [[Vanderbilt University School of Medicine]] Vanderbilt Prize for Women's Excellence in Science and Mentorship in 2014.<ref>{{cite web|url=https://biology.mit.edu/about/awards/2846|title=Recipients of Vanderbilt University School of Medicine Vanderbilt Prize for Women's Excellence in Science and Mentorship award|website=biology.mit.edu|access-date=October 30, 2016|url-status=dead|archive-url=https://web.archive.org/web/20161030143554/https://biology.mit.edu/about/awards/2846|archive-date=October 30, 2016}}</ref>
* Elected a [[List of Fellows of the Royal Society elected in 2015|Foreign Member of the Royal Society (ForMemRS)]] in 2015.<ref name="frs">{{cite web|url=https://royalsociety.org/people/susan-lindquist-11823|title=Susan Lindquist|publisher=Royal Society|access-date=October 30, 2016}}</ref><ref>{{cite web|url=https://royalsociety.org/about-us/fellowship/new-fellows-2015|title=Fellows Directory|publisher=Royal Society|access-date=October 30, 2016}}</ref>
* Vallee Visiting Professorship (2015)<ref>{{cite web |title=2015 Vallee Visiting Professors Announced |url=http://www.thevalleefoundation.org/news/2015-vallee-visiting-professors-announced |website=The Vallee Foundation |access-date=May 1, 2019|date= 2014}}</ref>
* Awarded the [[Albany Medical Center Prize in Medicine and Biomedical Research]] with F. Ulrich Hartl and Arthur Horwich in 2016.<ref name=":3">{{Cite web|url=http://wi.mit.edu/news/archive/2016/whitehead-s-susan-lindquist-receive-prestigious-albany-prize-medicine|title=Whitehead Institute – News – 2016 – Whitehead's Susan Lindquist to receive prestigious Albany Prize in Medicine|website=wi.mit.edu|date=August 3, 2016 |access-date=October 31, 2016}}</ref>
* Awarded (posthumously) the [[Rosenstiel Award]] in 2016.<ref>{{cite web|url=http://www.brandeis.edu/rosenstiel/rosenstielaward/current.html|title=Current Winner – Rosenstiel Award – Rosenstiel Basic Medical Sciences Research Center – Brandeis University|website=www.brandeis.edu}}</ref>
{{div col end}}

==Personal life==
Lindquist was married to Edward Buckbee and had two daughters.<ref name=":4">{{cite web|url=http://wi.mit.edu/news/archive/2016/susan-lindquist-accomplished-and-beloved-scientist-has-died-age-67|title=Whitehead Institute – News – 2016 – Susan Lindquist, accomplished and beloved scientist, has died at age 67|website=wi.mit.edu|date=October 28, 2016 |access-date=October 28, 2016}}</ref> She died of cancer in Boston at the age of 67 on October 27, 2016.<ref>{{cite news|url=https://www.nytimes.com/2016/10/30/science/susan-lindquist-scientist-who-made-genetic-discoveries-using-yeast-dies-at-67.html|title=Susan Lindquist Scientist Who Made Genetic Discoveries Using Yeast Dies at 67|newspaper=[[The New York Times]]|date=October 29, 2016 |access-date=October 30, 2016|last1=Grimes |first1=William }}</ref><ref name=obituary/>

==References==
{{Reflist|35em}}

{{FRS 2015}}
{{Authority control}}

{{DEFAULTSORT:Lindquist, Susan}}
[[Category:1949 births]]
[[Category:2016 deaths]]
[[Category:American geneticists]]
[[Category:American molecular biologists]]
[[Category:American people of Italian descent]]
[[Category:American people of Swedish descent]]
[[Category:American cell biologists]]
[[Category:Deaths from cancer in Massachusetts]]
[[Category:Fellows of the American Academy of Arts and Sciences]]
[[Category:Foreign members of the Royal Society]]
[[Category:Harvard University alumni]]
[[Category:Howard Hughes Medical Investigators]]
[[Category:Massachusetts Institute of Technology School of Science faculty]]
[[Category:Members of the National Academy of Medicine]]
[[Category:Members of the United States National Academy of Sciences]]
[[Category:People from Park Ridge, Illinois]]
[[Category:University of Illinois Urbana-Champaign alumni]]
[[Category:Whitehead Institute faculty]]
[[Category:American women molecular biologists]]
[[Category:Members of the American Philosophical Society]]
[[Category:Biologists from Illinois]]