Editing Tetanic contraction

{{Short description|Type of muscle contraction}}
{{plain image with caption|Wave summation and tetanus.png|caption=a) The excitation-contraction coupling effects of successive motor neuron signaling is added together which is referred to as wave summation. The bottom of each wave, the end of the relaxation phase, represents the point of stimulus. (b) When the stimulus frequency is so high that the relaxation phase disappears completely, the contractions become continuous; this is called tetanus.<ref name="Openstax Anatomy & Physiology attribution">{{CC-notice|cc=by4|url=https://openstax.org/books/anatomy-and-physiology/pages/9-introduction}} {{cite book|last1=Betts|first1=J Gordon|last2=Desaix|first2=Peter|last3=Johnson|first3=Eddie|last4=Johnson|first4=Jody E|last5=Korol|first5=Oksana|last6=Kruse|first6=Dean|last7=Poe|first7=Brandon|last8=Wise|first8=James|last9=Womble|first9=Mark D|last10=Young|first10=Kelly A|title=Anatomy & Physiology|location=Houston|publisher=OpenStax CNX|isbn=978-1-947172-04-3|date=June 7, 2023|url=https://openstax.org/books/anatomy-and-physiology/pages/10-4-nervous-system-control-of-muscle-tension|at=10.4 Nervous system control of muscle tension}}</ref>|aligh=right|caption position = bottom|upright=2}}
A '''tetanic contraction''' (also called '''tetanized state''', '''tetanus''', or '''physiologic tetanus''', the latter to differentiate from the disease called [[tetanus]]) is a sustained [[muscle contraction]]<ref>{{cite encyclopedia | encyclopedia = The American Heritage Medical Dictionary | isbn = 978-0-618-82435-9 | publisher = Houghton Mifflin Company | title = Tetanic | location = Boston Massachusetts | page = [https://archive.org/details/americanheritage00ahde/page/815 815] | date = 2007 | quote = Marked by sustained muscle contractions | url-access = registration | url = https://archive.org/details/americanheritage00ahde/page/815 }}</ref> evoked when the motor nerve that innervates a [[skeletal muscle]] emits action potentials at a very high rate.<ref name="Mann_2011">{{cite book | last1 = Mann | first1 = Michael D. | name-list-style = vanc | title = The Nervous System In Action | date = 2011 | publisher = Michael D. Mann | chapter = Chapter 14: Muscle Contraction: Twitch and tetanic contractions | chapter-url = http://michaeldmann.net/mann14.html | url-status = live | archiveurl = https://web.archive.org/web/20171105154542/http://michaeldmann.net/mann14.html | archivedate = 2017-11-05 }}</ref><ref name="Raf_2003">{{cite book | editor-last1 = Raff | editor-first1 = Hershel | title = Physiology Secrets | date = 2003 | publisher = Hanley & Belfus | location = Philadelphia, PA | isbn = 978-1-56053-509-6 | pages = 25–26 | edition = 2nd | first1 = Julian H. | last1 = Lombard | first2 = Nancy J. | last2 = Rush | name-list-style = vanc | chapter = Cells, Nerves, and Muscles | chapter-url = https://books.google.com/books?id=a1RchCrwKWsC&q=tetanic+contraction&pg=PA25 | url-status = live | archiveurl = https://web.archive.org/web/20160510203448/https://books.google.com/books?id=a1RchCrwKWsC&pg=PA25&dq=tetanic+contraction&hl=en&sa=X&ved=0ahUKEwiW2f6yoPfJAhVBdD4KHV2tC5YQ6AEILDAB#v=snippet&q=tetanic%20contraction&f=false | archivedate = 2016-05-10 }}</ref> During this state, a [[motor unit]] has been maximally stimulated by its [[motor neuron]] and remains that way for some time. This occurs when a muscle's motor unit is stimulated by multiple impulses at a sufficiently high frequency. Each stimulus causes a twitch. If stimuli are delivered slowly enough, the tension in the muscle will relax between successive twitches. If stimuli are delivered at high frequency, the twitches will overlap, resulting in tetanic contraction. A tetanic contraction can be either ''unfused (incomplete) or fused (complete)''.<ref name="muscular">{{cite web |title = Muscular System Part ii |url = https://windward.hawaii.edu/facstaff/miliefsky-m/ZOOL%20141L/muscular_system_part_ii_student.pdf |url-status = live |archiveurl = https://web.archive.org/web/20150927114252/http://windward.hawaii.edu/facstaff/miliefsky-m/ZOOL%20141L/muscular_system_part_ii_student.pdf |archivedate = 2015-09-27 }}</ref> An unfused tetanus is when the muscle fibers do not completely relax before the next stimulus because they are being stimulated at a fast rate; however there is a partial relaxation of the muscle fibers between the twitches.<ref name= "muscular"/> Fused tetanus is when there is no relaxation of the muscle fibers between stimuli and it occurs during a high rate of stimulation.<ref name= "muscular"/>  A fused tetanic contraction is the strongest single-unit twitch in contraction.<ref name="chap14">{{cite web |title=Chapter 14-Muscle Contraction. |url=http://michaeldmann.net/mann14.html |url-status=live |archiveurl=https://web.archive.org/web/20171105154542/http://michaeldmann.net/mann14.html |archivedate=2017-11-05 }}</ref> When tetanized, the contracting tension in the muscle remains constant in a [[steady state]]. This is the maximal possible contraction.<ref name="Mann_2011"/>  During tetanic contractions, muscles can shorten, lengthen or remain constant length.<ref name = "Widmaier et al 2008">{{cite book | last1 = Widmaier | first1 = Eric P. | last2 = Raff | first2 = Hersel | last3 = Strang | first3 = Kevin T. | name-list-style = vanc | chapter = Muscle | title = Vander's Human Physiology: The Mechanisms of Body Function | publisher = McGraw-Hill | edition = 12th | date = 2010 | location = New York, NY | pages = 250–291 | isbn = 978-0-321-98122-6}}</ref>

Tetanic contraction is usually normal (such as when holding up a heavy box). Muscles often exhibit some level of tetanic activity, leading to [[muscle tone]], in order to maintain posture;<ref name="pmid1579249">{{cite journal | vauthors = Davidoff RA | title = Skeletal muscle tone and the misunderstood stretch reflex | journal = Neurology | volume = 42 | issue = 5 | pages = 951–63 | year = 1992 | pmid = 1579249 | doi = 10.1212/WNL.42.5.951 | s2cid = 22317054 }}</ref> for example, in a crouching position, some muscles require sustained contraction to hold the position. Tetanic contraction can exist in a variety of states, including [[muscle contraction#Isotonic contraction|isotonic]] and [[muscle contraction#Isometric contraction|isometric]] forms—for example, lifting a heavy box off the floor is isotonic, but holding it at the elevated position is isometric. Isotonic contractions place muscles in a constant tension but the muscle length changes, while isometric contractions hold a constant muscle length.{{cn|date=August 2021}}

Voluntary sustained contraction is a normal (physiologic) process (as in the crouching or box-holding examples), but involuntary sustained contraction exists on a spectrum from physiologic to disordered (pathologic). Muscle tone is a healthy form of involuntary sustained ''partial'' contraction. In comparison with tetanic contraction in an isometric state (such as holding up a heavy box for several minutes), it differs only in the percentage of [[motor unit]]s participating at any moment and the frequency of neural signals; but the low percentage and low frequency in healthy tone are the key factors defining it as healthy (and not tetanic). Involuntary sustained contraction of a [[hypertonia|hypertonic]] type, however, is a pathologic process. On the mild part of the spectrum, [[cramp]]s, [[spasm]]s, and even [[tetany]] are often temporary and nonsevere. On the moderate to severe parts of the spectrum are [[dystonia]], [[trismus]], pathologic [[tetanus]], and other [[movement disorder]]s featuring involuntary sustained strong contractions of skeletal muscle.{{cn|date=August 2021}}

==See also==
* [[Muscle fatigue]]

==References==
{{reflist}}

[[Category:Electrophysiology]]
[[Category:Symptoms and signs: Nervous system]]
[[Category:Tetanus]]