Editing Tetanic stimulation

{{Short description|High frequency neuron stimulation}}
In [[neurobiology]], a '''tetanic stimulation''' consists of a high-frequency sequence of individual stimulations of a [[neuron]].{{Citation needed|date=February 2020|reason=The original source is now broken}} It is associated with [[long-term potentiation|potentiation]].

High-frequency stimulation causes an increase in release called post-tetanic potentiation (Kandel 2003).{{fact|date=October 2014}} This presynaptic event is caused by calcium influx. Calcium-protein interactions then produce a change in [[Synaptic vesicle|vesicle]] [[exocytosis]]. The result of these changes is to make the postsynaptic cell more likely to fire an [[action potential]]. 

Tetanic stimulation is used in medicine to detect a non-depolarizing block or a depolarizing block on the neuromuscular junction.<ref>{{cite web|last=Livingston|first=Churchill|title=Chapter 36:Tetanic stimulation|url=http://web.squ.edu.om/med-Lib/MED_CD/E_CDs/anesthesia/site/content/v03/030471r00.HTM|publisher=Sultan Qaboos University}}</ref> Lower elicitations of tetanic stimulation in aged muscles were shown to be caused by lower levels of anaerobic energy provision in [[skeletal muscle]]s.

==See also==
* [[Hebbian theory]]

==References==
{{reflist}}


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[[Category:Neurophysiologists]]

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[[de:Tetanisierung]]