Editing Zygote intrafallopian transfer

{{Short description|Embryos are laparoscopically transferred into fallopian tube}}
{{redirect|ZIFT|the 2008 Bulgarian film|Zift (film)}}
{{Infobox medical intervention |
  Name        = Zygote intrafallopian transfer |
  Image       = |
  Caption     = |
  ICD10       = |
  ICD9unlinked = |
  MeshID      = D017388 |
  OPS301      = |
  OtherCodes  = |
}}
'''Zygote intra fallopian transfer''' ('''ZIFT''') is an [[infertility treatment]] used when a blockage in the [[fallopian tube]]s prevents the normal binding of sperm to the egg. [[Egg cells]] are removed from a woman's [[ovaries]], and [[in vitro fertilisation|in vitro fertilised]]. The resulting [[zygote]] is placed into the [[fallopian tube]] by the use of [[laparoscopy]]. The procedure is a spin-off of the [[gamete intrafallopian transfer]] (GIFT) procedure. The pregnancy and implantation rates in ZIFT cycles are 52.3 and 23.2% which were higher than what was observed in IVF cycles which were 17.5 and 9.7%.<ref>{{Cite journal|last1=Boldt|first1=J.|last2=Schnarr|first2=P.|last3=Ajamie|first3=A.|last4=Ketner|first4=J.|last5=Bonaventura|first5=L.|last6=Colver|first6=R.|last7=Reuter|first7=L.|last8=Jarrett|first8=J.|date=November 1996|title=Success rates following intracytoplasmic sperm injection are improved by using ZIFT vs IVF for embryo transfer|url=https://pubmed.ncbi.nlm.nih.gov/8986589/|journal=Journal of Assisted Reproduction and Genetics|volume=13|issue=10|pages=782–785|doi=10.1007/BF02066498|issn=1058-0468|pmid=8986589|s2cid=12930938}}</ref>

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==Procedure==
The average ZIFT cycle takes five to six weeks to complete. First, the female must take a [[fertility medication]] clomiphene to [[ovulation induction|stimulate egg production]] in the ovaries. The doctor will monitor the growth of the [[ovarian follicles]], and once they are mature, the woman will receive an injection containing [[human chorionic gonadotropin]]s (HCG or hCG). The eggs will be harvested approximately 36 hours later, usually by [[transvaginal ovum retrieval]]. After fertilization in the laboratory, the resulting early embryos or zygotes are placed into the woman's fallopian tubes using a [[laparoscope]].

==Indications==
ZIFT has been used in infertility situations where at least one of the fallopian tubes is normal and other treatments have failed; however, the need for two interventions and the fact that [[IVF]] results are equal or better (as of 2004), leaves few indications for this procedure. Accordingly, the number of ZIFTs performed has been declining.<ref>{{cite journal |author=Toner JP| title=Progress we can be proud of: U.S. trends in assisted reproduction over the first 20 years. |journal=Fertil. Steril. | pmid=12413976 |year=2002 |volume=78 |issue=5 |pages=943–50 |doi=10.1016/s0015-0282(02)03769-x|doi-access=free }}</ref>

==References==
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{{Assisted reproductive technology}}
{{Reproductive health}}
{{Diseases of the pelvis and genitals}}

{{DEFAULTSORT:Zygote Intrafallopian Transfer}}
[[Category:Assisted reproductive technology]]
[[Category:Fertility medicine]]
[[Category:Fertility]]
[[Category:Female genital procedures]]