THB may refer to:
- Tanah Abang station
- Tetrahydrobiopterin, a chemical
- Tetrahydrocorticosterone, a hormone
- Thai baht, the currency of Thailand (ISO 4217 code: THB)
- THB (comics), and the character Tri-Hydro Bi-Oxygenate
- Three Horses Beer of Madagascar
- Toronto, Hamilton and Buffalo Railway reporting mark
- IATA code of Thaba Tseka Airport, an airport serving Thaba-Tseka in Lesotho
- ThB, Bachelor of Theology degree