Trevithick (Template:IPAc-en Template:Respell) is a Cornish surname. Notable people with the surname include:
- Francis Trevithick (1812–1877), one of the first locomotive engineers of the London and North Western Railway
- Jonathan Trevethick (1864–1939), New Zealand politician
- Paul Trevithick (born 1959), American inventor, engineer and entrepreneur
- Richard Trevithick (1771–1833), British inventor, mining engineer and builder of the first working railway steam locomotive
- William Edward Trevithick (1899–1958), Irish botanical illustrator