VLR could refer to:
- Visitor location register of a network switching subsystem
- Delahaye VLR passenger vehicle
- Vic Lee Racing
- Virginia Landmarks Register
- Victorian Law Reports
- Variable lymphocyte receptor
- Vallenar Airport IATA code VLR
- De Nederlandse Vereniging voor Lift- en Roltraptechniek (The Dutch Association of Lift and Escalator Engineering)
- Vive le Revolution group co-founded by Roland Castro
- Vellore Cantonment railway station
- Very Light Rail innovation center in Dudley, see its website
- Very Long Range aircraft, e.g. Consolidated B-24 Liberator
- Zero Escape: Virtue's Last Reward, a video game
- VLR, a forum page about the video game Valorant and the Valorant Esports scene
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