Meclofenoxate
Template:Short description Template:Drugbox
Meclofenoxate (INN, BAN; brand name Lucidril, also known as centrophenoxine) is a cholinergic nootropic used as a dietary supplement.<ref name="Elks2014">Template:Cite book</ref><ref>Template:Cite book</ref><ref name="ClinTox">Template:Cite journal</ref> It is an ester of dimethylethanolamine (DMAE) and 4-chlorophenoxyacetic acid (pCPA).
In elderly patients, meclofenoxate has been shown to improve performance on certain memory tests.<ref>Template:Cite journal</ref> Meclofenoxate also increases cellular membrane phospholipids.Template:Citation needed It is sold in Japan and some European countries, such as Germany, Hungary, and Austria, as a prescription drug.
Side effectsEdit
Meclofenoxate is considered to be safe and high in tolerability. However, possible side effects may include, rarely, insomnia, dizziness, restlessness, muscle tremor, depression, nausea, muscle tension, and headache; these side effects may be due to overdosage and may indicate the need for the dosage to be reduced.
ResearchEdit
Meclofenoxate, as well as DMAE, have been found to increase the lifespans of mice by 26.5%.<ref>Template:Cite book</ref><ref>Template:Cite journal</ref>
Brand namesEdit
In addition to Lucidril, meclofenoxate has also been marketed under the brand names Amipolen, Analux, Brenal, Cellative, Centrophenoxin, Cerebron, Cerutil, Closete, Helfergin, Lucidryl, Lutiaron, Marucotol, Proserout, Proseryl, and Ropoxyl.<ref name="Zhou2013">Template:Cite book</ref> In the US, meclofenoxate is sold as a dietary supplement, although it is an unapproved drug.<ref name="ClinTox" />
See alsoEdit
ReferencesEdit
Template:Antidementia Template:Acetylcholine receptor modulators