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Cephamycin
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{{Short description|Group of Ξ²-lactam antibiotics}} [[File:Cephamycin core structure.svg|thumb|250px|Core structure of the cephamycins.]] '''Cephamycins''' are a group of [[Ξ²-lactam antibiotic]]s. They are very similar to [[cephalosporin]]s, and the cephamycins are sometimes classified as cephalosporins. Like cephalosporins, cephamycins are based upon the [[cephem]] nucleus. Unlike most cephalosporins, cephamycins are a very efficient antibiotic against anaerobic microbes.{{cn|date=January 2023}} Cephamycins were originally produced by ''[[Streptomyces]]'', but synthetic ones have been produced as well.{{cn|date=January 2023}} Cephamycins possess a [[methoxy]] group at the 7-alpha position.<ref name="isbn1-55581-258-9">{{cite book |author=Oreste A. Mascaretti |title=Bacteria Versus Antibacterial Agents: An Integrated Approach |publisher=American Society Microbiology |year=2003 |pages=144 |isbn=1-55581-258-9 }}</ref> In addition, cephamycins have been shown to be stable against extended-spectrum beta-lactamase (ESBL) producing organisms, although their use in clinical practice is lacking for this indication.{{cn|date=January 2023}}
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